Rome2Rio

How to get fromLa Crosse to Effinghamby train (Amtrak), bus, car, plane, train, or bus (Greyhound)

Find Transport to Effingham

See all options

There are 6 ways to get from La Crosse to Effingham by train (Amtrak), bus, car, plane, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Effingham Stationtrain train Saluki / ...
    9h 49m
    $265–408

  2. Drive  420.6 mi

    cheapest
    1. Drive from La Crosse to Effinghamcar car 420.6 mi
    8h 46m
    $77–111

  3. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Water & Chicago - Circle K to Lupita's Grocery - Effinghambus bus Milwaukee
    10h 37m
    $115–155

  4. Fly to University Of Illinois Willard Airport, train

    1. Fly from La Crosse (LSE) to University Of Illinois Willard Airport (CMI)plane plane LSE - CMI
    2. Take the train from Champaign-Urbana to Effingham Stationtrain train
    7h 43m
    $121–439

  5. Bus via Chicago

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Effinghambus bus
    11h 28m
    $100–168

  6. Fly to Chicago O'Hare International Airport, train

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the train from Chicago Union Station to Effingham Stationtrain train
    7h 22m
    $163–439

La Crosse to Effingham by train (Amtrak)

Calendar21Weekly Trains
Duration9h 49mAverage Duration
Ticket$265Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from La Crosse to Effingham.ExpandLaunch map view
  • Distance: 479.4 mi
  • Duration: 9h 49m

What companies run services between La Crosse, WI, USA and Effingham, IL, USA?

You can take a train from La Crosse Amtrak Station to Effingham Station via Chicago Union Station in around 9h 49m. Alternatively, you can take a bus from La Crosse to Lupita's Grocery - Effingham via Milwaukee and Water & Chicago - Circle K in around 10h 37m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There