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How to get fromLa Crosse to Effinghamby train (Amtrak), bus, car, plane, train, or bus (Greyhound)

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There are 6 ways to get from La Crosse to Effingham by train (Amtrak), bus, car, plane, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Effingham Stationtrain train Saluki / ...
    9h 49m
    $156–313

  2. Drive 420.6 mi

    cheapest
    1. Drive from La Crosse to Effinghamcar car 420.6 mi
    8h 46m
    $77–111

  3. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    2. Take the bus from Water & Chicago - Circle K to Lupita's Grocery - Effinghambus bus Milwaukee
    11h 37m
    $123–250

  4. Fly to University Of Illinois Willard Airport, train

    1. Fly from La Crosse (LSE) to University Of Illinois Willard Airport (CMI)plane plane LSE - CMI
    2. Take the train from Champaign-Urbana to Effingham Stationtrain train
    7h 2m
    $109–404

  5. Bus via Chicago

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Effinghambus bus
    12h 9m
    $98–183

  6. Fly to Decatur Airport, bus, train

    1. Fly from La Crosse (LSE) to Decatur Airport (DEC)plane plane LSE - DEC
    2. Take the bus from Decatur Downtown Transportation Center to Champaign Intermodal Trans Ctrbus bus
    3. Take the train from Champaign-Urbana to Effingham Stationtrain train
    10h 31m
    $112–421

La Crosse to Effingham by train (Amtrak)

Calendar21Weekly Trains
Duration9h 49mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Effingham.ExpandLaunch map view
  • Distance: 479.4 mi
  • Duration: 9h 49m

What companies run services between La Crosse, WI, USA and Effingham, IL, USA?

You can take a train from La Crosse Amtrak Station to Effingham Station via Chicago Union Station in around 9h 49m. Alternatively, you can take a bus from La Crosse to Lupita's Grocery - Effingham via Milwaukee, WI - Amtrak and Water & Chicago - Circle K in around 11h 37m.

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