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How to get fromLa Crosse to Floridaby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 8 ways to get from La Crosse to Florida by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Jacksonville

    best
    1. Fly from La Crosse (LSE) to Jacksonville (JAX)plane plane LSE - JAX
    9h
    $129–574

  2. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    31h 25m
    $224–444

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    41h 48m
    $486–1,117

  4. Drive  1,263.7 mi

    1. Drive from La Crosse to Jacksonvillecar car 1,263.7 mi
    22h 39m
    $231–334

  5. Fly La Crosse to Tampa

    1. Fly from La Crosse (LSE) to Tampa (TPA)plane plane LSE - TPA
    6h 49m
    $140–623

  6. Fly La Crosse to Orlando

    1. Fly from La Crosse (LSE) to Orlando (MCO)plane plane LSE - MCO
    7h 32m
    $132–576

  7. Train to Minneapolis–Saint Paul International Airport, fly to Jacksonville

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Jacksonville (JAX)plane plane MSP - JAX
    9h 2m
    $177–732

  8. Train to Minneapolis–Saint Paul International Airport, fly to Tampa

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Tampa (TPA)plane plane MSP - TPA
    8h 42m
    $528–1,181

La Crosse to Florida by bus

Calendar7Weekly Buses
Duration31h 25mAverage Duration
Ticket$224Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Florida.ExpandLaunch map view
  • Distance: 1,087.4 mi
  • Duration: 9h

What companies run services between La Crosse, WI, USA and Florida, USA?

United Airlines, American Airlines, and two other airlines fly from La Crosse (LSE) to Jacksonville (JAX) 5 times a day. Alternatively, you can take a bus from La Crosse to Newnan St + Ashley St via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Atlanta Bus Station, Jacksonville, and JRTC Bay J in around 31h 25m.

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