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How to get fromLa Crosse to Fort Myersby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 6 ways to get from La Crosse to Fort Myers by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Ft. Myers (RSW)plane plane LSE - RSW
    8h 58m
    $151–626

  2. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    5. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    38h 5m
    $267–486

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    2d 3h
    $665–1,428

  4. Drive 1,510.4 mi

    1. Drive from La Crosse to Fort Myerscar car 1,510.4 mi
    26h 28m
    $276–399

  5. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Ft. Myers (RSW)plane plane MSN - RSW
    9h 59m
    $207–815

  6. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Ft. Myers (RSW)plane plane MSP - RSW
    9h 42m
    $197–793

La Crosse to Fort Myers by bus

Calendar7Weekly Buses
Duration38h 5mAverage Duration
Ticket$267Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Fort Myers.ExpandLaunch map view
  • Distance: 1,332.6 mi
  • Duration: 8h 58m

What companies run services between La Crosse, WI, USA and Fort Myers, FL, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Ft. Myers (RSW) 4 times a day. Alternatively, you can take a bus from La Crosse to Fort Myers Bus Stop via Milwaukee Intermodal Station, Chicago Bus Station, Atlanta Bus Station, and Tampa Bus Station in around 38h 5m.

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