Rome2Rio

How to get fromLa Crosse to Gainesvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Find Transport to Gainesville

See all options

There are 9 ways to get from La Crosse to Gainesville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Gainesville Regional Airport

    best
    1. Fly from La Crosse (LSE) to Gainesville Regional Airport (GNV)plane plane LSE - GNV
    9h 31m
    $120–493

  2. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    29h 2m
    $232–417

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    44h 24m
    $603–1,304

  4. Drive 1,284.2 mi

    1. Drive from La Crosse to Gainesvillecar car 1,284.2 mi
    22h 6m
    $235–339

  5. Fly La Crosse to Jacksonville, bus

    1. Fly from La Crosse (LSE) to Jacksonville (JAX)plane plane LSE - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    8h 59m
    $140–542

  6. Fly La Crosse to Orlando Sanford, drive

    1. Fly from La Crosse (LSE) to Orlando Sanford (SFB)plane plane LSE - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    5h 39m
    $138–531

  7. Bus to Dane County Regional Airport-Truax Field, fly to Gainesville Regional Airport

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Gainesville Regional Airport (GNV)plane plane MSN - GNV
    11h 41m
    $176–662

  8. Train to Minneapolis–Saint Paul International Airport, fly to Gainesville Regional Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Gainesville Regional Airport (GNV)plane plane MSP - GNV
    10h 42m
    $176–689

  9. Bus via Madison

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    32h 39m
    $230–440

La Crosse to Gainesville by bus

Calendar21Weekly Buses
Duration29h 2mAverage Duration
Ticket$232Cheapest Price
See schedules

Questions & Answers

Map of how to get from La Crosse to Gainesville.ExpandLaunch map view
  • Distance: 1,111.7 mi
  • Duration: 9h 31m

What companies run services between La Crosse, WI, USA and Gainesville, FL, USA?

American Airlines, Delta, and United Airlines fly from La Crosse (LSE) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from La Crosse to Gainesville via Milwaukee Intermodal Station, Chicago Bus Station, and Atlanta Bus Station in around 29h 2m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers