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How to get fromLa Crosse to Gainesvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 9 ways to get from La Crosse to Gainesville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Gainesville Regional Airport

    best
    1. Fly from La Crosse (LSE) to Gainesville Regional Airport (GNV)plane plane LSE - GNV
    9h 47m
    $115–503

  2. Bus via Milwaukee

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    29h 40m
    $229–379

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    44h 23m
    $1,015–1,656

  4. Drive  1,283.4 mi

    1. Drive from La Crosse to Gainesvillecar car 1,283.4 mi
    22h 8m
    $235–339

  5. Fly La Crosse to Jacksonville, bus

    1. Fly from La Crosse (LSE) to Jacksonville (JAX)plane plane LSE - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    9h 14m
    $139–590

  6. Bus to Dane County Regional Airport-Truax Field, fly to Gainesville Regional Airport

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Gainesville Regional Airport (GNV)plane plane MSN - GNV
    10h 19m
    $133–517

  7. Fly La Crosse to Orlando Sanford, drive

    1. Fly from La Crosse (LSE) to Orlando Sanford (SFB)plane plane LSE - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    5h 39m
    $138–541

  8. Train to Minneapolis–Saint Paul International Airport, fly to Gainesville Regional Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Gainesville Regional Airport (GNV)plane plane MSP - GNV
    10h 34m
    $195–714

  9. Bus

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus
    32h 59m
    $257–405

La Crosse to Gainesville by bus

Calendar7Weekly Buses
Duration29h 40mAverage Duration
Ticket$229Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Crosse to Gainesville.ExpandLaunch map view
  • Distance: 1,111.7 mi
  • Duration: 9h 47m

What companies run services between La Crosse, WI, USA and Gainesville, FL, USA?

American Airlines and Delta fly from La Crosse (LSE) to Gainesville Regional Airport (GNV) 3 times a day. Alternatively, you can take a bus from La Crosse to Gainesville via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Atlanta Bus Station in around 29h 40m.

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