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How to get fromLa Crosse to Graftonby train (Amtrak), bus, car, or plane

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There are 5 ways to get from La Crosse to Grafton by train (Amtrak), bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Milwaukeetrain train Empire Builder / ...
    3h 47m
    $115–197
  2. Drive 189.8 mi

    cheapest
    1. Drive from La Crosse to Graftoncar car 189.8 mi
    3h 58m
    $35–50
  3. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus Jefferson Lines 965
    5h 6m
    $84–114
  4. Fly to General Mitchell International Airport

    1. Fly from La Crosse (LSE) to General Mitchell International Airport (MKE)plane plane LSE - MKE
    6h 29m
    $116–499
  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 23m
    $90–328

La Crosse (LSE) to General Mitchell International Airport (MKE) flights

Calendar28Weekly Planes
Duration5h 10mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between La Crosse, WI, USA and Grafton, WI, USA?

Amtrak operates a train from La Crosse Amtrak Station to Milwaukee 3 times a day. Tickets cost $60–130 and the journey takes 3h 20m. Alternatively, Jefferson Lines operates a bus from La Crosse to Milwaukee once daily. Tickets cost $50–75 and the journey takes 3h 50m.

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