There are 6 ways to get from La Crosse to Indiana by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to South Bend
best- Fly from La Crosse (LSE) to South Bend (SBN)plane LSE - SBN
4h 10m$103–519Fly to Chicago O'Hare International Airport, train
cheapest- Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane LSE - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
3h 43m$62–285Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
11h 2m$126–286Bus via Milwaukee
- Take the bus from La Crosse to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Indianapolisbus
11h 10m$92–144Drive 459.7 mi
- Drive from La Crosse to Indianapoliscar 459.7 mi
7h 51m$84–122Bus
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Train Station to Indianapolis Union Stationbus
11h 47m$95–163
La Crosse to Indiana by train (Amtrak)
Questions & Answers
The cheapest way to get from La Crosse to Indiana is to drive which costs $80 - $130 and takes 7h 51m.
The fastest way to get from La Crosse to Indiana is to fly and train which takes 3h 43m and costs $60 - $290.
No, there is no direct bus from La Crosse to Indiana. However, there are services departing from La Crosse and arriving at Indianapolis via Milwaukee Intermodal Station and Chicago Bus Station. The journey, including transfers, takes approximately 11h 10m.
No, there is no direct train from La Crosse station to Indiana. However, there are services departing from La Crosse Amtrak Station and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 11h 2m.
The distance between La Crosse and Indiana is 305 miles. The road distance is 462.4 miles.
The best way to get from La Crosse to Indiana without a car is to train which takes 11h 2m and costs $120 - $290.
It takes approximately 4h 10m to get from La Crosse to Indiana, including transfers.
La Crosse to Indiana bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Indiana train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Indiana is to fly which takes 4h 10m and costs $100 - $550. Alternatively, you can train, which costs $120 - $290 and takes 11h 2m, you could also bus via Milwaukee, which costs $90 - $150 and takes 11h 10m.
What companies run services between La Crosse, WI, USA and Indiana, USA?
United Airlines and American Airlines fly from La Crosse (LSE) to South Bend (SBN) every 4 hours. Alternatively, you can take a train from La Crosse Amtrak Station to Indianapolis via Chicago Union Station in around 11h 2m.
- Website
- united.com
Flights from La Crosse to South Bend via Chicago O'Hare International Airport
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $70–480
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $35–250
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $75–170
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
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More Questions & Answers
La Crosse to Indiana bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Indiana is 1h ahead of La Crosse. It is currently 7:02 AM in La Crosse and 8:02 AM in Indiana.
La Crosse to Indiana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Indiana is 462 miles. It takes approximately 7h 51m to drive from La Crosse to Indiana.
Book your La Crosse to Indiana train tickets online with Omio.
There are 881+ hotels available in Indiana.







