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How to get fromLa Crosse to Iowa Cityby train, bus, bus (Greyhound), car, or plane

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There are 6 ways to get from La Crosse to Iowa City by train, bus, bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the bus from Chicago Bus Station to Iowa Citybus bus Greyhound US0123S / ...
    10h 32m
    $121–250

  2. Drive 176.3 mi

    cheapest
    1. Drive from La Crosse to Iowa Citycar car 176.3 mi
    3h 44m
    $33–47

  3. Bus

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    3. Take the bus from Des Moines to Iowa Citybus bus
    12h 45m
    $95–171

  4. Fly to The Eastern Iowa Airport, bus

    1. Fly from La Crosse (LSE) to The Eastern Iowa Airport (CID)plane plane LSE - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    7h 42m

  5. Bus via Chicago

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Iowa Citybus bus
    13h 20m
    $98–183

  6. Fly to Quad City International Airport, bus

    1. Fly from La Crosse (LSE) to Quad City International Airport (MLI)plane plane LSE - MLI
    2. Take the bus from Moline Center Station to Iowa Citybus bus
    8h 59m
    $78–359

La Crosse to Iowa City by train, foot, and bus

Calendar14Weekly Services
Duration10h 32mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Iowa City.ExpandLaunch map view
  • Distance: 503.2 mi
  • Duration: 10h 32m

What companies run services between La Crosse, WI, USA and Iowa City, IA, USA?

You can take a bus from La Crosse to Iowa City via St. Paul, Saint Paul Union Depot, and Des Moines in around 12h 45m.

Airlines
Train operators
Bus operators

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