There are 4 ways to get from La Crosse to Itasca by plane, bus, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane LSE - ORD
3h 28m$54–274Drive 262.3 mi
cheapest- Drive from La Crosse to Itascacar 262.3 mi
4h 20m$48–70Bus
- Take the bus from La Crosse to Madisonbus Jefferson Lines 965
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departuresbus Van Galder
6h 13m$102–158Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
6h 31m$159–243
La Crosse to Itasca by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from La Crosse to Itasca is to drive which costs $45 - $70 and takes 4h 20m.
The fastest way to get from La Crosse to Itasca is to fly which takes 3h 28m and costs $50 - $280.
No, there is no direct bus from La Crosse to Itasca. However, there are services departing from La Crosse and arriving at O'Hare International Airport - Terminal 1 Departures via 250 N. Lake St - Madison UW Campus. The journey, including transfers, takes approximately 6h 13m.
No, there is no direct train from La Crosse station to Itasca. However, there are services departing from La Crosse Amtrak Station and arriving at Itasca via Chicago Union Station. The journey, including transfers, takes approximately 6h 31m.
The distance between La Crosse and Itasca is 240 miles. The road distance is 263.8 miles.
The best way to get from La Crosse to Itasca without a car is to bus which takes 6h 13m and costs $100 - $160.
It takes approximately 3h 28m to get from La Crosse to Itasca, including transfers.
La Crosse to Itasca bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Itasca train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Itasca is to fly which takes 3h 28m and costs $50 - $280. Alternatively, you can bus, which costs $100 - $160 and takes 6h 13m, you could also train, which costs $150 - $250 and takes 6h 31m.
What companies run services between La Crosse, WI, USA and Itasca, IL, USA?
American Airlines flies from La Crosse (LSE) to Chicago O'Hare International Airport (ORD) 3 times a day. Alternatively, you can take a bus from La Crosse to Itasca via Madison, 250 N. Lake St - Madison UW Campus, and O'Hare International Airport - Terminal 1 Departures in around 6h 13m.
- Website
- aa.com
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $30–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
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Booking & Getting There
La Crosse to Itasca bus services, operated by Jefferson Lines, arrive at Madison station.
La Crosse to Itasca train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Itasca is 264 miles. It takes approximately 4h 20m to drive from La Crosse to Itasca.
There are 378+ hotels available in Itasca.







