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How to get fromLa Crosse to Jacksonby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

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There are 8 ways to get from La Crosse to Jackson by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Jackson/Vicksburg (JAN)plane plane LSE - JAN
    8h 16m
    $148–511

  2. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Jacksonbus bus
    21h 35m
    $178–321

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Jacksontrain train City of New Orleans
    21h 43m
    $320–674

  4. Drive 910 mi

    1. Drive from La Crosse to Jacksoncar car 910 mi
    15h 56m
    $167–240

  5. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Jackson/Vicksburg (JAN)plane plane MSP - JAN
    8h 54m
    $193–687

  6. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Jackson/Vicksburg (JAN)plane plane MSN - JAN
    9h 36m
    $211–755

  7. Bus to Appleton International Airport, fly

    1. Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus bus
    2. Fly from Appleton International Airport (ATW) to Jackson/Vicksburg (JAN)plane plane ATW - JAN
    11h 37m
    $190–577

  8. Bus, train

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Jacksontrain train
    23h 43m
    $295–603

La Crosse to Jackson by bus

Calendar7Weekly Buses
Duration21h 35mAverage Duration
Ticket$178Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Jackson.ExpandLaunch map view
  • Distance: 818.2 mi
  • Duration: 8h 16m

What companies run services between La Crosse, WI, USA and Jackson, MS, USA?

American Airlines, United Airlines, and two other airlines fly from La Crosse (LSE) to Jackson/Vicksburg (JAN) 5 times a day. Alternatively, you can take a bus from La Crosse to Jackson via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Memphis Bus Station in around 21h 35m.

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