There are 5 ways to get from La Crosse to Jefferson City by plane, train (Amtrak), bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from La Crosse (LSE) to Columbia Regional Airport (COU)plane LSE - COU
5h 28m$168–481Drive 418.2 mi
cheapest- Drive from La Crosse to Jefferson Citycar 418.2 mi
8h 8m$77–111Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Jefferson City Stationtrain Lincoln Service Missouri River Runner
13h 54m$209–454Bus
- Take the bus from La Crosse to St. Paulbus
- Take the bus from Saint Paul Union Depot to Kansas City Bus Stationbus
- Take the bus from Kansas City Bus Station to Jefferson Citybus
17h 48m$174–266Bus, train
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Jefferson City Stationtrain
15h 54m$185–383
La Crosse to Jefferson City by train (Amtrak)
Questions & Answers
The cheapest way to get from La Crosse to Jefferson City is to drive which costs $75 - $110 and takes 8h 8m.
The fastest way to get from La Crosse to Jefferson City is to fly which takes 5h 28m and costs $160 - $490.
No, there is no direct bus from La Crosse to Jefferson City. However, there are services departing from La Crosse and arriving at Jefferson City via Saint Paul Union Depot and Kansas City Bus Station. The journey, including transfers, takes approximately 17h 48m.
No, there is no direct train from La Crosse station to Jefferson City station. However, there are services departing from La Crosse Amtrak Station and arriving at Jefferson City Station via Chicago Union Station. The journey, including transfers, takes approximately 13h 54m.
The distance between La Crosse and Jefferson City is 384 miles. The road distance is 420.7 miles.
The best way to get from La Crosse to Jefferson City without a car is to train which takes 13h 54m and costs $200 - $460.
It takes approximately 5h 28m to get from La Crosse to Jefferson City, including transfers.
La Crosse to Jefferson City bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Jefferson City train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Jefferson City is to fly which takes 5h 28m and costs $160 - $490. Alternatively, you can train, which costs $200 - $460 and takes 13h 54m, you could also bus, which costs $170 - $270 and takes 17h 48m.
What companies run services between La Crosse, WI, USA and Jefferson City, MO, USA?
United Airlines and American Airlines fly from La Crosse (LSE) to Columbia Regional Airport (COU) 5 times a day. Alternatively, you can take a train from La Crosse Amtrak Station to Jefferson City Station via Chicago Union Station in around 13h 54m.
- Website
- aa.com
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $60–350
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 10h 34m
- When
- Every day
- Estimated price
- $130–550
- Website
- united.com
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $60–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $85–190
- Website
- Amtrak
Train from Chicago Union Station to Jefferson City Station
- Ave. Duration
- 7h 46m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- Amtrak
Train from Chicago Union Station to Jefferson City Station
- Ave. Duration
- 7h 46m
- Frequency
- Once daily
- Estimated price
- $120–270
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to St. Paul
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $40–65
- Book at
- Jefferson Lines
- Adult
- $40–65
Bus from Saint Paul Union Depot to Kansas City Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- 4 times a week
- Estimated price
- $100–150
- Book at
- Jefferson Lines
- Adult
- $100–150
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Saint Paul Union Depot to Kansas City Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- Twice daily
- Estimated price
- $65–130
- Website
- Greyhound
Bus from Kansas City Bus Station to Jefferson City
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
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More Questions & Answers
La Crosse to Jefferson City bus services, operated by Jefferson Lines, arrive at St. Paul station.
La Crosse to Jefferson City train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Jefferson City is 421 miles. It takes approximately 8h 8m to drive from La Crosse to Jefferson City.
Book your La Crosse to Jefferson City train tickets online with Omio.
Book your La Crosse to Jefferson City bus tickets online with Omio.
There are 19+ hotels available in Jefferson City.