There are 7 ways to get from La Crosse to Kalamazoo by train (Amtrak), bus (Amtrak), car, plane, bus (Flixbus, Greyhound), train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Kalamazootrain Wolverine / ...
8h 14m$230–357Fly to Kalamazoo-Battle Creek International Airport
cheapest- Fly from La Crosse (LSE) to Kalamazoo-Battle Creek International Airport (AZO)plane LSE - AZO
6h 38m$70–353Bus via Chicago
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Union Station to Kalamazoobus
10h 2mDrive 425.3 mi
- Drive from La Crosse to Kalamazoocar 425.3 mi
7h 10m$78–113Bus
- Take the bus from La Crosse to Madisonbus
- Take the bus from Madison to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Kalamazoo Bus Stopbus
11h 25m$92–138Fly to Chicago O'Hare International Airport, train
- Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane LSE - ORD
- Take the train from Chicago Union Station to Kalamazootrain
5h 47m$128–389Fly to Gerald R. Ford International Airport, bus
- Fly from La Crosse (LSE) to Gerald R. Ford International Airport (GRR)plane LSE - GRR
- Take the bus from Grand Rapids to Kalamazoobus
9h 18m$82–379
La Crosse to Kalamazoo by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from La Crosse to Kalamazoo is to drive which costs $75 - $120 and takes 7h 10m.
The fastest way to get from La Crosse to Kalamazoo is to fly and train which takes 5h 47m and costs $120 - $390.
No, there is no direct bus from La Crosse to Kalamazoo. However, there are services departing from La Crosse and arriving at Kalamazoo via 250 N. Lake St - Madison UW Campus and Chicago Union Station. The journey, including transfers, takes approximately 10h 2m.
No, there is no direct train from La Crosse station to Kalamazoo. However, there are services departing from La Crosse Amtrak Station and arriving at Kalamazoo via Chicago Union Station. The journey, including transfers, takes approximately 8h 14m.
The distance between La Crosse and Kalamazoo is 419 miles. The road distance is 427.8 miles.
The best way to get from La Crosse to Kalamazoo without a car is to train which takes 8h 14m and costs $230 - $360.
It takes approximately 8h 14m to get from La Crosse to Kalamazoo, including transfers.
La Crosse to Kalamazoo bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Kalamazoo train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Kalamazoo is to train which takes 8h 14m and costs $230 - $360. Alternatively, you can bus via Chicago, which costs and takes 10h 2m, you could also fly, which costs $70 - $360 and takes 6h 38m.
What companies run services between La Crosse, WI, USA and Kalamazoo, MI, USA?
You can take a train from La Crosse Amtrak Station to Kalamazoo via Chicago Union Station in around 8h 14m. Alternatively, you can take a bus from La Crosse to Kalamazoo via Madison, 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 10h 2m.
- Website
- aa.com
Flights from La Crosse to Kalamazoo-Battle Creek International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $50–330
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $30–240
Flights from La Crosse to Gerald R. Ford International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $50–330
- Website
- allegiantair.com
Flights from La Crosse to Gerald R. Ford International Airport via Orlando Sanford
- Ave. Duration
- 10h 28m
- When
- Sunday and Thursday
- Estimated price
- $160–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $75–120
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 3 times a week
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $27–40
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Madison to Chicago Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Greyhound
Bus from Chicago Bus Station to Kalamazoo Bus Stop
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $26–40
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Grand Rapids to Kalamazoo
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $10–24
- Website
- Indian Trails
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
La Crosse to Kalamazoo bus services, operated by Jefferson Lines, arrive at Madison station.
Kalamazoo is 1h ahead of La Crosse. It is currently 2:55 PM in La Crosse and 3:55 PM in Kalamazoo.
La Crosse to Kalamazoo train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Kalamazoo is 428 miles. It takes approximately 7h 10m to drive from La Crosse to Kalamazoo.
Book your La Crosse to Kalamazoo train tickets online with Omio.
Book your La Crosse to Kalamazoo bus tickets online with Omio.
There are 52+ hotels available in Kalamazoo.











