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How to get fromLa Crosse to Key Westby plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

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There are 5 ways to get from La Crosse to Key West by plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from La Crosse (LSE) to Key West International Airport (EYW)plane plane LSE - EYW
    5h 56m
    $129–484

  2. Bus

    1. Take the bus from University of Wisconsin - La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Miamibus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    6. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 7h
    $386–676

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    2d 12h
    $766–1,633

  4. Drive 1,754.3 mi

    1. Drive from La Crosse to Key Westcar car 1,754.3 mi
    31h 13m
    $321–463

  5. Bus, train, shuttle

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to West Palm Beach Amtrak Stationtrain train
    4. Take the bus from West Palm Beach, FL to Fort Lauderdale Airportbus bus
    5. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FLshuttle bus
    2d 14h
    $911–1,664

La Crosse to Key West by bus, taxi, and foot

Calendar4Weekly Services
Duration2d 7hAverage Duration
Ticket$386Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Key West.ExpandLaunch map view
  • Distance: 1,447.7 mi
  • Duration: 5h 56m

What companies run services between La Crosse, WI, USA and Key West, FL, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Key West International Airport (EYW) 3 times a day. Alternatively, you can take a bus from University of Wisconsin - La Crosse to N Roosevelt & 3rd Street via Milwaukee Intermodal Station, Chicago Bus Station, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 2d 7h.

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