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How to get fromLa Crosse to Lafayetteby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

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There are 8 ways to get from La Crosse to Lafayette by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Lafayette Regional Airport

    best
    1. Fly from La Crosse (LSE) to Lafayette Regional Airport (LFT)plane plane LSE - LFT
    8h 1m
    $139–584

  2. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Lafayettebus bus
    28h 25m
    $233–411

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Lafayette Amtrak Stationtrain train
    30h 14m
    $422–928

  4. Drive 1,087.1 mi

    1. Drive from La Crosse to Lafayettecar car 1,087.1 mi
    21h 17m
    $199–287

  5. Bus to Dane County Regional Airport-Truax Field, fly to Lafayette Regional Airport

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Lafayette Regional Airport (LFT)plane plane MSN - LFT
    9h 27m
    $192–768

  6. Fly La Crosse to Louis Armstrong New Orleans International Airport, bus

    1. Fly from La Crosse (LSE) to Louis Armstrong New Orleans International Airport (MSY)plane plane LSE - MSY
    2. Take the bus from New Orleans International Airport to Lafayette Transit Systembus bus
    11h 6m
    $149–666

  7. Train to Minneapolis–Saint Paul International Airport, fly to Lafayette Regional Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lafayette Regional Airport (LFT)plane plane MSP - LFT
    9h 31m
    $173–700

  8. Bus, train

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Lafayette Amtrak Stationtrain train
    32h 14m
    $400–858

La Crosse to Lafayette by bus

Calendar5Weekly Buses
Duration28h 25mAverage Duration
Ticket$233Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Lafayette.ExpandLaunch map view
  • Distance: 954.6 mi
  • Duration: 8h 1m

What companies run services between La Crosse, WI, USA and Lafayette, LA, USA?

American Airlines, United Airlines, and Delta fly from La Crosse (LSE) to Lafayette Regional Airport (LFT) every 4 hours. Alternatively, you can take a bus from La Crosse to Lafayette via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Memphis Bus Station in around 28h 25m.

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