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How to get fromLa Crosse to Manhattanby plane, train, car, or bus (Greyhound)

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There are 5 ways to get from La Crosse to Manhattan by plane, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from La Crosse (LSE) to Manhattan Regional Airport (MHK)plane plane LSE - MHK
    5h 23m
    $123–461

  2. Drive 541.5 mi

    cheapest
    1. Drive from La Crosse to Manhattancar car 541.5 mi
    10h 15m
    $99–143

  3. Train, drive (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Topeka Stationtrain train
    3. Drive from Topeka Station to Manhattancar car
    16h 42m
    $248–530

  4. Bus

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from Saint Paul Union Depot to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City Bus Station to Manhattan KSbus bus
    17h 55m
    $167–255

  5. Bus via Minneapolis Airport (MSP)

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from Minneapolis-St. Paul to Kansas Citybus bus
    3. Take the bus from Kansas City Bus Station to Manhattan KSbus bus
    19h 4m
    $169–258

La Crosse to Manhattan by bus

Calendar7Weekly Buses
Duration17h 55mAverage Duration
Ticket$167Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Manhattan.ExpandLaunch map view
  • Distance: 444.7 mi
  • Duration: 5h 23m

What companies run services between La Crosse, WI, USA and Manhattan, KS, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Manhattan Regional Airport (MHK) 5 times a day. Alternatively, you can take a bus from La Crosse to Manhattan KS via Saint Paul Union Depot and Kansas City Bus Station in around 17h 55m.

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