There are 6 ways to get from La Crosse to Manitowoc by train, bus, bus (Greyhound), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from La Crosse Amtrak Station to Milwaukeetrain Empire Builder / ...
- Take the bus from Milwaukee to Manitowocbus It 58
5h 58m$74–166Drive 208.8 mi
cheapest- Drive from La Crosse to Manitowoccar 208.8 mi
4h 32m$39–55Bus
- Take the bus from La Crosse to Milwaukeebus Jefferson Lines 965
- Take the bus from Milwaukee to Manitowocbus It 58
6h 28m$75–105Fly La Crosse to Appleton International Airport, taxi
- Fly from La Crosse (LSE) to Appleton International Airport (ATW)plane LSE - ATW
- Take the taxi from Appleton International Airport (ATW) to Manitowoctaxi
5h 31m$178–491Fly La Crosse to Green Bay, bus
- Fly from La Crosse (LSE) to Green Bay (GRB)plane LSE - GRB
- Take the bus from Green Bay Transit Center to Manitowocbus
7h 35m$118–437Train to Minneapolis–Saint Paul International Airport, fly to Appleton International Airport, taxi
- Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Appleton International Airport (ATW)plane MSP - ATW
- Take the taxi from Appleton International Airport (ATW) to Manitowoctaxi
7h 1m$202–613
La Crosse (LSE) to Appleton International Airport (ATW) flights
Comparing Your Travel Options
The cheapest way to get from La Crosse to Manitowoc is to drive which costs $35 - $55 and takes 4h 32m.
The fastest way to get from La Crosse to Manitowoc is to drive which takes 4h 32m and costs $35 - $55.
No, there is no direct bus from La Crosse to Manitowoc. However, there are services departing from La Crosse and arriving at Manitowoc via Milwaukee. The journey, including transfers, takes approximately 6h 28m.
The distance between La Crosse and Manitowoc is 279 miles. The road distance is 210 miles.
The best way to get from La Crosse to Manitowoc without a car is to train and bus which takes 5h 58m and costs $70 - $170.
It takes approximately 5h 58m to get from La Crosse to Manitowoc, including transfers.
La Crosse to Manitowoc bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Manitowoc bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Yes, the driving distance between La Crosse to Manitowoc is 210 miles. It takes approximately 4h 32m to drive from La Crosse to Manitowoc.
Book your La Crosse to Manitowoc bus tickets online with Omio.
What companies run services between La Crosse, WI, USA and Manitowoc, WI, USA?
You can take a bus from La Crosse to Manitowoc via Milwaukee and Manitowoc in around 6h 28m.
- Website
- aa.com
Flights from La Crosse to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $50–330
Flights from La Crosse to Green Bay via Chicago O'Hare
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $50–340
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Appleton International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $55–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Milwaukee
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- $50–140
- Website
- Amtrak
Train from La Crosse Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 2h 52m
- Frequency
- 3 times a day
- Estimated price
- $35–90
- Website
- Amtrak
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Milwaukee to Manitowoc
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Indian Trails
Bus from Milwaukee to Manitowoc
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Indian Trails
Bus from Green Bay Transit Center to Manitowoc
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $8–22
- Website
- Indian Trails
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee to Manitowoc
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Milwaukee to Manitowoc
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Green Bay Transit Center to Manitowoc
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $6–10
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Ave. Duration
- 1h 11m
- Estimated price
- $110–140
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Want to know more about travelling around United States
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Booking & Getting There
There are 27+ hotels available in Manitowoc.










