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How to get fromLa Crosse to Mequonby train (Amtrak), bus, car, or plane

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There are 5 ways to get from La Crosse to Mequon by train (Amtrak), bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Milwaukeetrain train Empire Builder / ...
    3h 50m
    $104–178
  2. Drive 189.8 mi

    cheapest
    1. Drive from La Crosse to Mequoncar car 189.8 mi
    3h 54m
    $35–50
  3. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    5h 56m
    $75–103
  4. Fly to General Mitchell International Airport

    1. Fly from La Crosse (LSE) to General Mitchell International Airport (MKE)plane plane LSE - MKE
    6h 19m
    $108–461
  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    5h 25m
    $96–375

La Crosse (LSE) to General Mitchell International Airport (MKE) flights

Calendar28Weekly Planes
Duration5h 10mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between La Crosse, WI, USA and Mequon, WI, USA?

Amtrak operates a train from La Crosse Amtrak Station to Milwaukee 3 times a day. Tickets cost $60–130 and the journey takes 3h 20m. Alternatively, Jefferson Lines operates a bus from La Crosse to Milwaukee, WI - Amtrak 3 times a day. Tickets cost $55–80 and the journey takes 4h 50m.

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