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How to get fromLa Crosse to Mesaby plane, train, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from La Crosse to Mesa by plane, train, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Phoenix

    best
    1. Fly from La Crosse (LSE) to Phoenix (PHX)plane plane LSE - PHX
    8h 19m
    $150–573

  2. Fly La Crosse to Phoenix-Mesa Gateway Airport

    cheapest
    1. Fly from La Crosse (LSE) to Phoenix-Mesa Gateway Airport (AZA)plane plane LSE - AZA
    5h 46m
    $134–577

  3. Train, bus via Flagstaff

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Flagstafftrain train
    3. Take the bus from Flagstaff Train Station to Tempebus bus
    42h 13m
    $669–1,330

  4. Bus

    1. Take the bus from La Crosse to Rochester, MNbus bus
    2. Take the bus from Rochester to Owatonnabus bus
    3. Take the bus from Owatonna to Tulsabus bus
    4. Take the bus from Tulsa Bus Station to Phoenix Bus Stationbus bus
    43h 22m

  5. Drive 1,618.8 mi

    1. Drive from La Crosse to Mesacar car 1,618.8 mi
    29h 2m
    $296–427

  6. Train to Minneapolis–Saint Paul International Airport, fly to Phoenix

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Phoenix (PHX)plane plane MSP - PHX
    8h 42m
    $196–589

  7. Bus to Dane County Regional Airport-Truax Field, fly to Phoenix

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Phoenix (PHX)plane plane MSN - PHX
    9h 35m
    $216–662

  8. Bus to Rochester, fly to Phoenix

    1. Take the bus from La Crosse to Rochester, MNbus bus
    2. Fly from Rochester (RST) to Phoenix (PHX)plane plane RST - PHX
    10h 1m
    $240–991

  9. Bus via Denver

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    5. Take the bus from Las Vegas Strip to Tempebus bus
    2d 8h

  10. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tucson Amtrak Stationtrain train
    3. Take the bus from Tucson Downtown to Tempebus bus
    2d 16h
    $811–1,714

La Crosse to Mesa by train, bus, and tram

Calendar5Weekly Services
Duration42h 13mAverage Duration
Ticket$669Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Mesa.ExpandLaunch map view
  • Distance: 1,344.8 mi
  • Duration: 8h 19m

What companies run services between La Crosse, WI, USA and Mesa, AZ, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Phoenix (PHX) 5 times a day. Alternatively, you can take a bus from La Crosse to Mesa Dr/Main St via Rochester, Owatonna, Tulsa Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 43h 22m.

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