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How to get fromLa Crosse to Milwaukeeby train (Amtrak), bus, car, or plane

Find Transport to Milwaukee

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There are 5 ways to get from La Crosse to Milwaukee by train (Amtrak), bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Milwaukeetrain train Empire Builder / ...
    3h 20m
    $50–120
  2. Drive  209.5 mi

    cheapest
    1. Drive from La Crosse to Milwaukeecar car 209.5 mi
    3h 31m
    $39–56
  3. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus Jefferson Lines 965
    3h 50m
    $50–75
  4. Fly to General Mitchell International Airport

    1. Fly from La Crosse (LSE) to General Mitchell International Airport (MKE)plane plane LSE - MKE
    4h 48m
    $86–464
  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    4h 7m
    $62–286

La Crosse to Milwaukee by train (Amtrak)

Calendar21Weekly Trains
Duration3h 20mAverage Duration
Ticket$50Cheapest Price
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Comparing Your Travel Options

What companies run services between La Crosse, WI, USA and Milwaukee, WI, USA?

Amtrak operates a train from La Crosse Amtrak Station to Milwaukee 3 times a day. Tickets cost $50–120 and the journey takes 3h 20m. Alternatively, Jefferson Lines operates a bus from La Crosse to Milwaukee once daily. Tickets cost $50–75 and the journey takes 3h 50m.

Airlines
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Bus operators

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