There are 7 ways to get from La Crosse to Missouri by plane, bus, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Columbia Regional Airport
best- Fly from La Crosse (LSE) to Columbia Regional Airport (COU)plane LSE - COU
5h 19m$128–436Drive 430.7 mi
cheapest- Drive from La Crosse to Kansas Citycar 430.7 mi
8h 11m$79–114Bus
- Take the bus from La Crosse to Rochester, MNbus
- Take the bus from Rochester to Albert Leabus
- Take the bus from Albert Lea to Kansas Citybus
12h 5mTrain (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
13h 43m$231–473Fly to Lambert–St. Louis International Airport
- Fly from La Crosse (LSE) to Lambert–St. Louis International Airport (STL)plane LSE - STL
5h 28m$106–514Fly to Springfield-Branson National Airport
- Fly from La Crosse (LSE) to Springfield-Branson National Airport (SGF)plane LSE - SGF
4h 32m$104–411Fly to Kansas City
- Fly from La Crosse (LSE) to Kansas City (MCI)plane LSE - MCI
6h 20m$128–621
La Crosse (LSE) to Columbia Regional Airport (COU) flights
Questions & Answers
The cheapest way to get from La Crosse to Missouri is to drive which costs $75 - $120 and takes 8h 11m.
The fastest way to get from La Crosse to Missouri is to fly which takes 4h 32m and costs $100 - $420.
No, there is no direct bus from La Crosse to Missouri. However, there are services departing from La Crosse and arriving at Kansas City via Rochester and Albert Lea. The journey, including transfers, takes approximately 12h 5m.
No, there is no direct train from La Crosse station to Missouri. However, there are services departing from La Crosse Amtrak Station and arriving at Metro Center via Chicago Union Station and Union Station. The journey, including transfers, takes approximately 13h 43m.
The distance between La Crosse and Missouri is 375 miles. The road distance is 433.2 miles.
The best way to get from La Crosse to Missouri without a car is to bus which takes 12h 5m and costs .
It takes approximately 5h 19m to get from La Crosse to Missouri, including transfers.
La Crosse to Missouri bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Missouri train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Missouri is to fly which takes 5h 19m and costs $120 - $440. Alternatively, you can bus, which costs and takes 12h 5m, you could also train, which costs $230 - $480 and takes 13h 43m.
What companies run services between La Crosse, WI, USA and Missouri, USA?
United Airlines and American Airlines fly from La Crosse (LSE) to Columbia Regional Airport (COU) 5 times a day. Alternatively, you can take a bus from La Crosse to Kansas City via Rochester and Albert Lea in around 12h 5m.
- Website
- aa.com
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $60–350
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 10h 34m
- When
- Every day
- Estimated price
- $130–550
Flights from La Crosse to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $85–490
Flights from La Crosse to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $70–370
Flights from La Crosse to Kansas City via Chicago O'Hare
- Ave. Duration
- 7h 51m
- When
- Every day
- Estimated price
- $110–600
- Website
- united.com
Flights from La Crosse to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $60–350
Flights from La Crosse to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $85–490
Flights from La Crosse to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $70–370
Flights from La Crosse to Kansas City via Chicago O'Hare
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $140–290
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Rochester, MN
- Ave. Duration
- 1h 40m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Albert Lea to Kansas City
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $85–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $85–120
- Website
- example.com
Bus from Rochester to Albert Lea
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Schedules at
- example.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
La Crosse to Missouri bus services, operated by Jefferson Lines, arrive at Rochester, MN station.
La Crosse to Missouri train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Missouri is 433 miles. It takes approximately 8h 11m to drive from La Crosse to Missouri.
There are 399+ hotels available in Missouri.