There are 6 ways to get from La Crosse to Mitchell by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
- Take the bus from Minneapolis to Sioux Fallsbus
- Take the bus from Sioux Falls to Mitchellbus
12h 6m$136–228Drive 363.1 mi
cheapest- Drive from La Crosse to Mitchellcar 363.1 mi
5h 46m$67–96Fly from La Crosse, bus
- Fly from La Crosse (LSE) to Sioux Falls (FSD)plane LSE - FSD
- Take the bus from Sioux Falls to Mitchellbus
7h 16m$124–454Bus
- Take the bus from La Crosse to Minneapolisbus
- Take the bus from Minneapolis to Sioux Fallsbus
- Take the bus from Sioux Falls to Mitchellbus
12h 25m$137–204Train to Minneapolis–Saint Paul International Airport, fly, bus
- Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Sioux Falls (FSD)plane MSP - FSD
- Take the bus from Sioux Falls to Mitchellbus
7h 46m$126–471Bus to Rochester, fly, bus
- Take the bus from La Crosse to Rochester, MNbus
- Fly from Rochester (RST) to Sioux Falls (FSD)plane RST - FSD
- Take the bus from Sioux Falls to Mitchellbus
9h 7m$150–682
La Crosse (LSE) to Sioux Falls (FSD) flights
Questions & Answers
The cheapest way to get from La Crosse to Mitchell is to drive which costs $65 - $100 and takes 5h 46m.
The fastest way to get from La Crosse to Mitchell is to drive which takes 5h 46m and costs $65 - $100.
No, there is no direct bus from La Crosse to Mitchell. However, there are services departing from La Crosse and arriving at Mitchell via Minneapolis and Sioux Falls. The journey, including transfers, takes approximately 12h 25m.
The distance between La Crosse and Mitchell is 486 miles. The road distance is 365.3 miles.
The best way to get from La Crosse to Mitchell without a car is to train and bus which takes 12h 6m and costs $130 - $230.
It takes approximately 12h 6m to get from La Crosse to Mitchell, including transfers.
La Crosse to Mitchell bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Mitchell bus services, operated by Jefferson Lines, arrive at Minneapolis station.
Yes, the driving distance between La Crosse to Mitchell is 365 miles. It takes approximately 5h 46m to drive from La Crosse to Mitchell.
There are 14+ hotels available in Mitchell.
What companies run services between La Crosse, WI, USA and Mitchell, SD, USA?
You can take a bus from La Crosse to Mitchell via Minneapolis and Sioux Falls in around 12h 25m.
- Website
- delta.com
Flights from Minneapolis–Saint Paul International Airport to Sioux Falls
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $45–330
Flights from Rochester to Sioux Falls via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $85–550
- Website
- aa.com
Flights from La Crosse to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $70–380
Flights from Rochester to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $140–750
- Website
- united.com
Flights from La Crosse to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $70–380
Flights from Rochester to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from La Crosse Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 2h 52m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Train from La Crosse Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 2h 52m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Minneapolis to Sioux Falls
- Ave. Duration
- 5h 25m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–100
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from La Crosse to Minneapolis
- Ave. Duration
- 3h 55m
- Frequency
- Twice daily
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
Bus from Minneapolis to Sioux Falls
- Ave. Duration
- 5h 25m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–100
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from La Crosse to Rochester, MN
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide







