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How to get fromLa Crosse to Mitchellby train, bus, car, or plane

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There are 6 ways to get from La Crosse to Mitchell by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train Empire Builder / ...
    2. Take the bus from Minneapolis to Mitchellbus bus Jefferson Lines 701
    11h 36m
    $117–199

  2. Drive 363.1 mi

    cheapest
    1. Drive from La Crosse to Mitchellcar car 363.1 mi
    5h 46m
    $67–96

  3. Fly from La Crosse, bus

    1. Fly from La Crosse (LSE) to Sioux Falls (FSD)plane plane LSE - FSD
    2. Take the bus from Sioux Falls to Mitchellbus bus
    7h 17m
    $124–464

  4. Bus

    1. Take the bus from La Crosse to Minneapolisbus bus Jefferson Lines 966
    2. Take the bus from Minneapolis to Mitchellbus bus Jefferson Lines 701
    12h 20m
    $126–183

  5. Train to Minneapolis–Saint Paul International Airport, fly, bus

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Sioux Falls (FSD)plane plane MSP - FSD
    3. Take the bus from Sioux Falls to Mitchellbus bus
    7h 46m
    $118–482

  6. Bus to Rochester, fly, bus

    1. Take the bus from La Crosse to Rochesterbus bus
    2. Fly from Rochester (RST) to Sioux Falls (FSD)plane plane RST - FSD
    3. Take the bus from Sioux Falls to Mitchellbus bus
    9h 27m
    $110–442

La Crosse to Mitchell by train and bus

Calendar7Weekly Services
Duration11h 36mAverage Duration
Ticket$117Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Mitchell.ExpandLaunch map view
  • Distance: 481.8 mi
  • Duration: 11h 36m

What companies run services between La Crosse, WI, USA and Mitchell, SD, USA?

You can take a bus from La Crosse to Mitchell via Minneapolis in around 12h 20m.

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