There are 9 ways to get from La Crosse to Mobile by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly La Crosse to Mobile Regional Airport
best- Fly from La Crosse (LSE) to Mobile Regional Airport (MOB)plane LSE - MOB
9h 13m$143–541Fly La Crosse to Pensacola International Airport, bus
cheapest- Fly from La Crosse (LSE) to Pensacola International Airport (PNS)plane LSE - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
9h 8m$97–406Bus
- Take the bus from La Crosse to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus
28h 21m$204–332Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
29h 33m$329–793Drive 1,062.1 mi
- Drive from La Crosse to Mobilecar 1,062.1 mi
19h 48m$194–280Bus to Dane County Regional Airport-Truax Field, fly to Mobile Regional Airport
- Take the bus from La Crosse to Madisonbus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Mobile Regional Airport (MOB)plane MSN - MOB
9h 14m$201–795Fly La Crosse to Destin–Fort Walton Beach Airport, drive
- Fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS)plane LSE - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar
7h 20m$127–509Train to Minneapolis–Saint Paul International Airport, fly to Destin–Fort Walton Beach Airport, drive
- Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Destin–Fort Walton Beach Airport (VPS)plane MSP - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar
9h 20m$163–706Bus, train
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
31h 21m$325–743
La Crosse to Mobile by bus
Comparing Your Travel Options
The cheapest way to get from La Crosse to Mobile is to fly and bus which costs $95 - $410 and takes 9h 8m.
The fastest way to get from La Crosse to Mobile is to fly and drive which takes 7h 20m and costs $120 - $550.
No, there is no direct bus from La Crosse to Mobile. However, there are services departing from La Crosse and arriving at Govt EB Mid Block Past Joachim St via Milwaukee Intermodal Station, Chicago Bus Station, Nashville Bus Station, Montgomery Intermodal Center and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 28h 21m.
No, there is no direct train from La Crosse station to Mobile. However, there are services departing from La Crosse Amtrak Station and arriving at Mobile Amtrak Sta via Chicago Union Station and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 29h 33m.
The distance between La Crosse and Mobile is 952 miles. The road distance is 1068.3 miles.
The best way to get from La Crosse to Mobile without a car is to bus which takes 28h 21m and costs $200 - $340.
It takes approximately 9h 13m to get from La Crosse to Mobile, including transfers.
La Crosse to Mobile bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Mobile train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Mobile is to fly which takes 9h 13m and costs $140 - $550. Alternatively, you can bus, which costs $200 - $340 and takes 28h 21m, you could also train, which costs $320 - $800 and takes 29h 33m.
What companies run services between La Crosse, WI, USA and Mobile, AL, USA?
United Airlines, American Airlines, and Delta fly from La Crosse (LSE) to Mobile Regional Airport (MOB) every 4 hours. Alternatively, you can take a bus from La Crosse to Govt EB Mid Block Past Joachim St via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Nashville Bus Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 28h 21m.
- Website
- aa.com
Flights from La Crosse to Mobile Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 13h 41m
- When
- Every day
- Estimated price
- $110–550
Flights from La Crosse to Mobile Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 13h 23m
- When
- Every day
- Estimated price
- $120–600
Flights from Dane County Regional Airport-Truax Field to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $170–800
Flights from Dane County Regional Airport-Truax Field to Mobile Regional Airport via Charlotte
- Ave. Duration
- 7h 51m
- When
- Every day
- Estimated price
- $150–750
Flights from La Crosse to Pensacola International Airport via Chicago O'Hare
- Ave. Duration
- 7h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–370
Flights from La Crosse to Destin–Fort Walton Beach Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Saturday
- Estimated price
- $90–460
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $65–170
- Website
- Amtrak
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $230–550
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Amtrak
Train from La Crosse Amtrak Station to St. Paul-Minneapolis
- Ave. Duration
- 2h 52m
- Frequency
- 3 times a day
- Estimated price
- $30–75
- Website
- Amtrak
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $230–550
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
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Booking & Getting There
La Crosse to Mobile bus services, operated by Jefferson Lines, arrive at Milwaukee station.
La Crosse to Mobile train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Mobile is 1068 miles. It takes approximately 19h 48m to drive from La Crosse to Mobile.
Book your La Crosse to Mobile train tickets online with Omio.
There are 216+ hotels available in Mobile.







