There are 8 ways to get from La Crosse to Mobile by plane, car, bus (Greyhound, Flixbus), train (Amtrak), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly La Crosse to Destin–Fort Walton Beach Airport, drive
best- Fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS)plane LSE - VPS
- Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar
11h 25m$132–509Fly La Crosse to Pensacola International Airport, bus
cheapest- Fly from La Crosse (LSE) to Pensacola International Airport (PNS)plane LSE - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
9h 23m$101–408Bus
- Take the bus from La Crosse to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus
28h 39m$191–354Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
29h 33m$355–800Drive 1,062.1 mi
- Drive from La Crosse to Mobilecar 1,062.1 mi
19h 48m$194–280Fly La Crosse to Mobile Regional Airport
- Fly from La Crosse (LSE) to Mobile Regional Airport (MOB)plane LSE - MOB
11h 1m$118–501Bus to Dane County Regional Airport-Truax Field, fly to Mobile Regional Airport
- Take the bus from La Crosse to Madisonbus
- Fly from Dane County Regional Airport-Truax Field (MSN) to Mobile Regional Airport (MOB)plane MSN - MOB
11h 27m$161–705Bus, train
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain
31h 22m$345–748
La Crosse to Mobile by bus
Questions & Answers
The cheapest way to get from La Crosse to Mobile is to bus which costs $190 - $360 and takes 28h 39m.
The fastest way to get from La Crosse to Mobile is to fly and bus which takes 9h 23m and costs $100 - $410.
No, there is no direct bus from La Crosse to Mobile. However, there are services departing from La Crosse and arriving at Water NB at St Louis St via Milwaukee Intermodal Station, Chicago Bus Station, Nashville Bus Station, Montgomery Intermodal Center and Govt EB at Greyhound Bus Station. The journey, including transfers, takes approximately 28h 39m.
No, there is no direct train from La Crosse station to Mobile. However, there are services departing from La Crosse Amtrak Station and arriving at Mobile Amtrak Sta via Chicago Union Station and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 29h 33m.
The distance between La Crosse and Mobile is 1079 miles. The road distance is 1068.3 miles.
The best way to get from La Crosse to Mobile without a car is to bus which takes 28h 39m and costs $190 - $360.
It takes approximately 11h 25m to get from La Crosse to Mobile, including transfers.
La Crosse to Mobile bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Mobile train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Mobile is to bus which takes 28h 39m and costs $190 - $360. Alternatively, you can train, which costs $350 - $800 and takes 29h 33m, you could also fly, which costs $110 - $500 and takes 11h 1m.
What companies run services between La Crosse, WI, USA and Mobile, AL, USA?
You can take a bus from La Crosse to Water NB at St Louis St via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Nashville Bus Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 28h 39m. Alternatively, you can take a train from La Crosse Amtrak Station to Mobile Amtrak Sta via Chicago Union Station and New Orleans Union Passenger Terminal in around 29h 33m.
- Website
- aa.com
Flights from La Crosse to Destin–Fort Walton Beach Airport via Chicago O'Hare
- Ave. Duration
- 17h 21m
- When
- Every day
- Estimated price
- $95–460
Flights from La Crosse to Pensacola International Airport via Chicago O'Hare
- Ave. Duration
- 7h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–370
Flights from La Crosse to Mobile Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 10h 14m
- When
- Thursday and Sunday
- Estimated price
- $110–550
Flights from La Crosse to Mobile Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 11h 16m
- When
- Every day
- Estimated price
- $130–600
Flights from Dane County Regional Airport-Truax Field to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $160–750
Flights from Dane County Regional Airport-Truax Field to Mobile Regional Airport via Charlotte
- Ave. Duration
- 8h 26m
- When
- Every day
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $75–170
- Website
- Amtrak
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $250–550
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- Amtrak
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $250–550
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Mobile Amtrak Sta
- Ave. Duration
- 2h 43m
- Frequency
- Twice daily
- Estimated price
- $30–85
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
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More Questions & Answers
La Crosse to Mobile bus services, operated by Jefferson Lines, arrive at Milwaukee station.
La Crosse to Mobile train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Mobile is 1068 miles. It takes approximately 19h 48m to drive from La Crosse to Mobile.
Book your La Crosse to Mobile train tickets online with Omio.
There are 198+ hotels available in Mobile.







