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How to get fromLa Crosse to Naplesby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 7 ways to get from La Crosse to Naples by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from La Crosse

    best
    1. Fly from La Crosse (LSE) to Ft. Myers (RSW)plane plane LSE - RSW
    12h 46m
    $152–629

  2. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to University of South Floridabus bus
    5. Take the bus from University of South Florida - 3801 USF Holly Dr to Naples, FLbus bus
    36h 51m
    $300–543

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Tampatrain train
    3. Take the bus from University of South Florida - 3801 USF Holly Dr to Naples, FLbus bus
    2d 4h
    $705–1,500

  4. Drive 1,544.1 mi

    1. Drive from La Crosse to Naplescar car 1,544.1 mi
    27h 5m
    $282–407

  5. Bus to Dane County Regional Airport-Truax Field, fly

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Ft. Myers (RSW)plane plane MSN - RSW
    12h 57m
    $205–813

  6. Train to Minneapolis–Saint Paul International Airport, fly

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Ft. Myers (RSW)plane plane MSP - RSW
    13h 30m
    $197–796

  7. Bus to Rochester, fly

    1. Take the bus from La Crosse to Rochesterbus bus
    2. Fly from Rochester (RST) to Ft. Myers (RSW)plane plane RST - RSW
    16h 56m
    $163–687

La Crosse (LSE) to Ft. Myers (RSW) flights

Calendar28Weekly Planes
Duration8h 53mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Naples.ExpandLaunch map view
  • Distance: 1,363.8 mi
  • Duration: 12h 46m

What companies run services between La Crosse, WI, USA and Naples, FL, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Ft. Myers (RSW) 4 times a day. Alternatively, you can take a bus from La Crosse to Naples via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Atlanta Bus Station, University of South Florida - 3801 USF Holly Dr, and Naples, FL in around 36h 51m.

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