There are 5 ways to get from La Crosse to Niles by plane, train (Amtrak), bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane LSE - ORD
2h 15m$51–269Drive 268.8 mi
cheapest- Drive from La Crosse to Nilescar 268.8 mi
4h 30m$50–71Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Glenview Amtrak Stationtrain Empire Builder / ...
5h 26m$85–176Bus
- Take the bus from La Crosse to Milwaukeebus Jefferson Lines 965
- Take the bus from Milwaukee Intermodal Station to Chicagobus Greyhound US0150
6h 45m$67–101Bus via Madison
- Take the bus from La Crosse to Madisonbus Jefferson Lines 965
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus Van Galder
6h 49m$65–111
La Crosse to Niles by train and bus (Amtrak)
Questions & Answers
The cheapest way to get from La Crosse to Niles is to drive which costs $45 - $75 and takes 4h 30m.
The fastest way to get from La Crosse to Niles is to fly which takes 2h 15m and costs $50 - $270.
No, there is no direct bus from La Crosse to Niles. However, there are services departing from La Crosse and arriving at Touhy Ave & Milwaukee Ave via Milwaukee Intermodal Station and Cumberland CTA Station. The journey, including transfers, takes approximately 6h 45m.
No, there is no direct train from La Crosse station to Niles station. However, there are services departing from La Crosse Amtrak Station and arriving at Glenview Amtrak Station via . The journey, including transfers, takes approximately 5h 26m.
The distance between La Crosse and Niles is 235 miles. The road distance is 270.4 miles.
The best way to get from La Crosse to Niles without a car is to train which takes 5h 26m and costs $85 - $180.
It takes approximately 2h 15m to get from La Crosse to Niles, including transfers.
La Crosse to Niles bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Niles train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Niles is to fly which takes 2h 15m and costs $50 - $270. Alternatively, you can train, which costs $85 - $180 and takes 5h 26m, you could also bus, which costs $65 - $110 and takes 6h 45m.
What companies run services between La Crosse, WI, USA and Niles, IL, USA?
American Airlines and United Airlines fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD) 4 times a day. Alternatively, Amtrak operates a train from La Crosse Amtrak Station to Glenview Amtrak Station 3 times a day. Tickets cost $80–180 and the journey takes 4h 35m.
- Website
- aa.com
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $30–240
- Website
- united.com
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $30–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Glenview Amtrak Station
- Ave. Duration
- 4h 35m
- Frequency
- 3 times a day
- Estimated price
- $80–180
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
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More Questions & Answers
La Crosse to Niles bus services, operated by Jefferson Lines, arrive at Milwaukee station.
La Crosse to Niles train services, operated by Amtrak, arrive at Glenview Amtrak Station.
Yes, the driving distance between La Crosse to Niles is 270 miles. It takes approximately 4h 30m to drive from La Crosse to Niles.
There are 1141+ hotels available in Niles.









