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How to get fromLa Crosse to North Carolinaby plane, bus (Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from La Crosse to North Carolina by plane, bus (Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from La Crosse (LSE) to Piedmont Triad International Airport (GSO)plane plane LSE - GSO
    5h 56m
    $176–756

  2. Fly to Raleigh-Durham International Airport

    cheapest
    1. Fly from La Crosse (LSE) to Raleigh-Durham International Airport (RDU)plane plane LSE - RDU
    6h 24m
    $116–504

  3. Bus via Columbus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Hurricanebus bus
    4. Take the bus from Hurricane to Charlotte Bus Stationbus bus
    26h 53m
    $170–328

  4. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    34h 58m
    $482–1,047

  5. Drive 1,009.4 mi

    1. Drive from La Crosse to Charlottecar car 1,009.4 mi
    18h 7m
    $185–267

  6. Fly to Charlotte Douglas International Airport

    1. Fly from La Crosse (LSE) to Charlotte Douglas International Airport (CLT)plane plane LSE - CLT
    5h 45m
    $141–674

  7. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    28h 2m
    $203–381

La Crosse to North Carolina by bus and foot

Calendar7Weekly Services
Duration26h 53mAverage Duration
Ticket$170Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to North Carolina.ExpandLaunch map view
  • Distance: 821.1 mi
  • Duration: 5h 56m

What companies run services between La Crosse, WI, USA and North Carolina, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to Piedmont Triad International Airport (GSO) every 4 hours. Alternatively, you can take a bus from La Crosse to Charlotte Bus Station via Milwaukee, Milwaukee Intermodal Station, Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus - Mound St, and Hurricane in around 26h 53m.

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