There are 8 ways to get from La Crosse to Ohio by plane, train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cleveland-Hopkins International Airport
best- Fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE)plane LSE - CLE
5h 13m$101–504Fly to Dayton
cheapest- Fly from La Crosse (LSE) to Dayton (DAY)plane LSE - DAY
6h 46m$75–373Train, bus
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the bus from Chicago Bus Station to Columbusbus FlixBus 2511 / ...
13h 37m$124–248Train, bus via Toledo
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Toledotrain
- Take the bus from Toledo to Columbus - Mound Stbus
13h 57m$155–343Drive 590.4 mi
- Drive from La Crosse to Columbuscar 590.4 mi
10h 56m$108–156Fly to Covington
- Fly from La Crosse (LSE) to Covington (CVG)plane LSE - CVG
6h 6m$116–626Bus
- Take the bus from La Crosse to Milwaukeebus Jefferson Lines 965
- Take the bus from Milwaukee Intermodal Station to Columbusbus FlixBus 2511
14h 40m$120–185Bus via Chicago
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago to Limabus
- Take the bus from Lima to Columbusbus
16h 48m$97–223
La Crosse to Ohio by train, foot, and bus
Questions & Answers
The cheapest way to get from La Crosse to Ohio is to drive which costs $100 - $160 and takes 10h 56m.
The fastest way to get from La Crosse to Ohio is to fly which takes 5h 13m and costs $100 - $550.
No, there is no direct bus from La Crosse to Ohio. However, there are services departing from La Crosse and arriving at Columbus via Milwaukee Intermodal Station. The journey, including transfers, takes approximately 14h 40m.
The distance between La Crosse and Ohio is 529 miles. The road distance is 593.8 miles.
The best way to get from La Crosse to Ohio without a car is to train and bus which takes 13h 37m and costs $120 - $250.
It takes approximately 5h 13m to get from La Crosse to Ohio, including transfers.
La Crosse to Ohio bus services, operated by Jefferson Lines, depart from La Crosse station.
The best way to get from La Crosse to Ohio is to fly which takes 5h 13m and costs $100 - $550. Alternatively, you can bus, which costs $120 - $190 and takes 14h 40m.
La Crosse to Ohio bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Ohio is 1h ahead of La Crosse. It is currently 2:34 AM in La Crosse and 3:34 AM in Ohio.
What companies run services between La Crosse, WI, USA and Ohio, USA?
United Airlines and American Airlines fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE) 4 times a day. Alternatively, you can take a bus from La Crosse to Columbus via Milwaukee and Milwaukee Intermodal Station in around 14h 40m.
- Website
- aa.com
Flights from La Crosse to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $80–480
Flights from La Crosse to Dayton via Chicago O'Hare
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $55–350
Flights from La Crosse to Covington via Chicago O'Hare
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $95–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $70–170
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $70–170
- Website
- Amtrak
Train from Chicago Union Station to Toledo
- Ave. Duration
- 3h 59m
- Frequency
- 3 times a day
- Estimated price
- $60–140
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Columbus
- Ave. Duration
- 7h 20m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
Bus from Milwaukee Intermodal Station to Columbus
- Ave. Duration
- 9h 50m
- Frequency
- 6 times a week
- Estimated price
- $65–110
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Yes, the driving distance between La Crosse to Ohio is 594 miles. It takes approximately 10h 56m to drive from La Crosse to Ohio.
There are 581+ hotels available in Ohio.





