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How to get fromLa Crosse to Ohioby plane, train, bus, car, or bus (Flixbus)

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There are 8 ways to get from La Crosse to Ohio by plane, train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE)plane plane LSE - CLE
    5h 39m
    $111–514

  2. Drive 590.4 mi

    cheapest
    1. Drive from La Crosse to Columbuscar car 590.4 mi
    10h 55m
    $108–156

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    13h 37m
    $176–303

  4. Train, bus via Toledo

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Toledotrain train
    3. Take the bus from Toledo to Columbus - Mound Stbus bus
    13h 57m
    $188–388

  5. Fly to Dayton

    1. Fly from La Crosse (LSE) to Dayton (DAY)plane plane LSE - DAY
    5h 47m
    $170–923

  6. Fly to Covington

    1. Fly from La Crosse (LSE) to Covington (CVG)plane plane LSE - CVG
    6h 26m
    $111–526

  7. Bus

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    2. Take the bus from Milwaukee Intermodal Station to Columbusbus bus FlixBus 2511
    15h 40m
    $128–200

  8. Bus via Chicago

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago to Limabus bus
    4. Take the bus from Lima to Columbusbus bus
    17h 29m
    $139–253

La Crosse to Ohio by train, foot, and bus

Calendar21Weekly Services
Duration13h 37mAverage Duration
Ticket$176Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Ohio.ExpandLaunch map view
  • Distance: 526.4 mi
  • Duration: 5h 39m

What companies run services between La Crosse, WI, USA and Ohio, USA?

United Airlines and American Airlines fly from La Crosse (LSE) to Cleveland-Hopkins International Airport (CLE) 4 times a day. Alternatively, you can take a bus from La Crosse to Columbus via Milwaukee Intermodal Station in around 15h 40m.

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