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How to get fromLa Crosse to Paducahby plane, bus, train, or car

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There are 6 ways to get from La Crosse to Paducah by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Williamson County Regional Airport, bus

    best
    1. Fly from La Crosse (LSE) to Williamson County Regional Airport (MWA)plane plane LSE - MWA
    2. Take the bus from Carbondale Intermodal Station to Paducah Bus Stationbus bus
    6h 48m
    $133–451

  2. Drive 571.1 mi

    cheapest
    1. Drive from La Crosse to Paducahcar car 571.1 mi
    11h 4m
    $105–151

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Paducah Bus Stationbus bus
    13h 57m
    $212–423

  4. Bus

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Paducah Bus Stationbus bus
    19h 14m

  5. Fly to Barkley Regional Airport

    1. Fly from La Crosse (LSE) to Barkley Regional Airport (PAH)plane plane LSE - PAH
    7h 41m
    $109–403

  6. Fly to Cape Girardeau Municipal Airport, drive

    1. Fly from La Crosse (LSE) to Cape Girardeau Municipal Airport (CGI)plane plane LSE - CGI
    2. Drive from Cape Girardeau Municipal Airport (CGI) to Paducahcar car
    8h 57m
    $161–641

La Crosse (LSE) to Williamson County Regional Airport (MWA) flights

Calendar19Weekly Planes
Duration5h 14mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Paducah.ExpandLaunch map view
  • Distance: 532.1 mi
  • Duration: 6h 48m

What companies run services between La Crosse, WI, USA and Paducah, KY, USA?

You can take a bus from La Crosse to Paducah via 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, Chicago Bus Station, and Paducah Bus Station in around 19h 14m. Alternatively, American Airlines and United Airlines fly from La Crosse (LSE) to Barkley Regional Airport (PAH) twice daily.

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