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How to get fromLa Crosse to Panama City Beachby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 9 ways to get from La Crosse to Panama City Beach by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Northwest Florida Beaches International Airport

    best
    1. Fly from La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP)plane plane LSE - ECP
    5h 31m
    $163–536

  2. Fly La Crosse to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from La Crosse (LSE) to Destin–Fort Walton Beach Airport (VPS)plane plane LSE - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    6h 30m
    $123–487

  3. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville Bus Station to Tallahasseebus bus
    5. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    30h 54m
    $232–423

  4. Train, bus via New Orleans

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    33h 54m
    $433–936

  5. Drive 1,167 mi

    1. Drive from La Crosse to Panama City Beachcar car 1,167 mi
    20h 45m
    $213–308

  6. Fly La Crosse to Pensacola International Airport, bus

    1. Fly from La Crosse (LSE) to Pensacola International Airport (PNS)plane plane LSE - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    8h 25m
    $127–462

  7. Bus to Dane County Regional Airport-Truax Field, fly to Northwest Florida Beaches International Airport

    1. Take the bus from La Crosse to Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Northwest Florida Beaches International Airport (ECP)plane plane MSN - ECP
    9h 8m
    $211–720

  8. Bus via Atlanta

    1. Take the bus from La Crosse to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    5. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    34h 44m
    $229–450

  9. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus
    2d 1h
    $629–1,379

La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP) flights

Calendar25Weekly Planes
Duration7h 8mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Panama City Beach.ExpandLaunch map view
  • Distance: 1,006.4 mi
  • Duration: 5h 31m

What companies run services between La Crosse, WI, USA and Panama City Beach, FL, USA?

American Airlines, United Airlines, and Southwest Airlines fly from La Crosse (LSE) to Northwest Florida Beaches International Airport (ECP) 4 times a day. Alternatively, you can take a bus from La Crosse to Panama City Beach via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Nashville Bus Station, Tallahassee, and Panama City Beach Bus Station in around 30h 54m.

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