There are 7 ways to get from La Crosse to Purdue University by train (Amtrak), bus (Flixbus), car, plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain Empire Builder / ...
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain Cardinal
9h 39m$220–347Drive 401.3 mi
cheapest- Drive from La Crosse to Purdue Universitycar 401.3 mi
6h 52m$69–100Bus
- Take the bus from La Crosse to Madisonbus Jefferson Lines 965
- Take the bus from Madison to Lafayette Bus Stopbus FlixBus 2514
10h$80–119Fly to Chicago O'Hare International Airport, shuttle
- Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane LSE - ORD
- Take a shuttle bus from O'Hare International Terminal 2 to West Lafayette, IN
6h 12m$83–321Bus, shuttle
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departuresbus
- Take a shuttle bus from O'Hare International Terminal 2 to West Lafayette, IN
10h 32m$92–163Fly to Indianapolis, bus
- Fly from La Crosse (LSE) to Indianapolis (IND)plane LSE - IND
- Take the bus from Indianapolis Airport to Co-Rec Circle Drivebus
7h 29m$127–551Fly to Purdue University Airport
- Fly from La Crosse (LSE) to Purdue University Airport (LAF)plane LSE - LAF
5h 7m$69–352
La Crosse to Purdue University by train, bus, and foot (Amtrak)
Comparing Your Travel Options
The cheapest way to get from La Crosse to Purdue University is to drive which costs $65 - $100 and takes 6h 52m.
The fastest way to get from La Crosse to Purdue University is to fly which takes 5h 7m and costs $65 - $360.
No, there is no direct bus from La Crosse to Purdue University. However, there are services departing from La Crosse and arriving at First Street Towers on Mitch Daniels Blvd: BUS898 via Madison and CityBus Center: BUS215. The journey, including transfers, takes approximately 10h.
No, there is no direct train from La Crosse station to Purdue University station. However, there are services departing from La Crosse Amtrak Station and arriving at Lafayette Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 9h 39m.
The distance between La Crosse and Purdue University is 405 miles. The road distance is 403.7 miles.
The best way to get from La Crosse to Purdue University without a car is to train which takes 9h 39m and costs $220 - $350.
It takes approximately 9h 39m to get from La Crosse to Purdue University, including transfers.
La Crosse to Purdue University bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Purdue University train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Purdue University is to train which takes 9h 39m and costs $220 - $350. Alternatively, you can bus, which costs $75 - $120 and takes 10h, you could also fly, which costs $65 - $360 and takes 5h 7m.
What companies run services between La Crosse, WI, USA and Purdue University, IN, USA?
You can take a train from La Crosse Amtrak Station to Purdue University via Chicago Union Station, Lafayette Amtrak Station, Columbia St & 2nd St, and First Street Towers on Mitch Daniels Blvd: BUS898 in around 9h 39m. Alternatively, you can take a bus from La Crosse to Purdue University via Madison, Lafayette Bus Stop, CityBus Center: BUS215, and First Street Towers on Mitch Daniels Blvd: BUS898 in around 10h.
- Website
- aa.com
Flights from La Crosse to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $35–240
Flights from La Crosse to Indianapolis via Chicago O'Hare International Airport
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $80–490
- Website
- united.com
Flights from La Crosse to Purdue University Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $50–330
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Madison to Lafayette Bus Stop
- Ave. Duration
- 6h
- Frequency
- 6 times a week
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from O'Hare International Terminal 2 to West Lafayette, IN
- Ave. Duration
- 3h 51m
- Frequency
- On demand
- Estimated price
- $30–56
- Schedules at
- lafayettelimo.com
- Child
- $30–50
- Adult
- $51–56
Shuttle from O'Hare International Terminal 2 to West Lafayette, IN
- Ave. Duration
- 3h 51m
- Frequency
- On demand
- Estimated price
- $30–56
- Schedules at
- lafayettelimo.com
- Child
- $30–50
- Adult
- $51–56
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
- Phone
- +1 765-637-5124
- [email protected]
- Website
- Reindeer Shuttle
Bus from Indianapolis Airport to Co-Rec Circle Drive
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $29–37
- Website
- Reindeer Shuttle
- Online Advance
- $29–32
- Walk up Cash
- $33–37
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
La Crosse to Purdue University bus services, operated by Jefferson Lines, arrive at Madison station.
Purdue University is 1h ahead of La Crosse. It is currently 4:45 AM in La Crosse and 5:45 AM in Purdue University.
La Crosse to Purdue University train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Purdue University is 404 miles. It takes approximately 6h 52m to drive from La Crosse to Purdue University.
There are 51+ hotels available in Purdue University.















