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How to get fromLa Crosse to Quad Citiesby train, bus, car, or plane

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There are 6 ways to get from La Crosse to Quad Cities by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Take the bus from St. Paul to Duluthbus bus
    3. Take the bus from Duluth to Virginiabus bus
    8h 35m
    $144–219

  2. Drive  298.5 mi

    cheapest
    1. Drive from La Crosse to Quad Citiescar car 298.5 mi
    5h 47m
    $51–74

  3. Train to Minneapolis–Saint Paul International Airport, fly to Range Regional Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Range Regional Airport (HIB)plane plane MSP - HIB
    6h 13m
    $183–557

  4. Bus

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from St. Paul to Duluthbus bus
    3. Take the bus from Duluth to Virginiabus bus
    9h 8m
    $117–170

  5. Bus to Rochester, fly to Range Regional Airport

    1. Take the bus from La Crosse to Rochesterbus bus
    2. Fly from Rochester (RST) to Range Regional Airport (HIB)plane plane RST - HIB
    7h 48m
    $134–474

  6. Train to Minneapolis–Saint Paul International Airport, fly to International Falls, drive

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to International Falls (INL)plane plane MSP - INL
    3. Drive from International Falls (INL) to Quad Citiescar car
    7h 41m
    $144–526

Minneapolis–Saint Paul International Airport (MSP) to Range Regional Airport (HIB) flights

Calendar12Weekly Planes
Duration1h 9mAverage Duration
Ticket$53Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Crosse to Quad Cities.ExpandLaunch map view
  • Distance: 348.4 mi
  • Duration: 8h 35m

What companies run services between La Crosse, WI, USA and Quad Cities, MN, USA?

You can take a bus from La Crosse to Quad Cities via St. Paul, Duluth, and Virginia in around 9h 8m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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