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How to get fromLa Crosse to Rochesterby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus)

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There are 6 ways to get from La Crosse to Rochester by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from La Crosse (LSE) to Rochester (ROC)plane plane LSE - ROC
    6h 24m
    $153–690

  2. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Rochestertrain train Lake Shore Limited
    17h 38m
    $281–573

  3. Bus via Chicago

    1. Take the bus from La Crosse to Milwaukee, WI - Amtrakbus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Rochester Bus Stopbus bus
    21h 57m
    $162–303

  4. Drive 876.2 mi

    1. Drive from La Crosse to Rochestercar car 876.2 mi
    15h 3m
    $160–231

  5. Fly to Buffalo Niagara International Airport, bus

    1. Fly from La Crosse (LSE) to Buffalo Niagara International Airport (BUF)plane plane LSE - BUF
    2. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    6h 23m
    $164–711

  6. Bus

    1. Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus bus
    2. Take the bus from Appleton Transit Center to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Torontobus bus
    4. Take the bus from Toronto to Rochesterbus bus
    28h 20m
    $200–368

La Crosse to Rochester by train (Amtrak)

Calendar14Weekly Trains
Duration17h 38mAverage Duration
Ticket$281Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Rochester.ExpandLaunch map view
  • Distance: 693.4 mi
  • Duration: 6h 24m

What companies run services between La Crosse, WI, USA and Rochester, NY, USA?

United Airlines and American Airlines fly from La Crosse (LSE) to Rochester (ROC) 3 times a day. Alternatively, you can take a train from La Crosse Amtrak Station to Rochester via Chicago Union Station in around 17h 38m.

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