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How to get fromLa Crosse to San Antonioby plane, bus, train (Amtrak), car, or train

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There are 7 ways to get from La Crosse to San Antonio by plane, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to San Antonio International Airport

    best
    1. Fly from La Crosse (LSE) to San Antonio International Airport (SAT)plane plane LSE - SAT
    7h 3m
    $170–723

  2. Bus

    1. Take the bus from La Crosse to Milwaukeebus bus
    2. Take the bus from Water & Chicago - Circle K to Dallasbus bus
    3. Take the bus from Tornado Bus Co - Dallas I-30 to Tornado Bus Co - San Antoniobus bus
    32h 21m
    $282–557

  3. Train (Amtrak)

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to San Antonio Stationtrain train Texas Eagle
    38h 44m
    $499–1,084

  4. Drive 1,191.8 mi

    1. Drive from La Crosse to San Antoniocar car 1,191.8 mi
    20h 55m
    $218–315

  5. Fly La Crosse to Austin-Bergstrom International Airport, bus

    1. Fly from La Crosse (LSE) to Austin-Bergstrom International Airport (AUS)plane plane LSE - AUS
    2. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    8h 56m
    $181–748

  6. Train to Minneapolis–Saint Paul International Airport, fly to San Antonio International Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to San Antonio International Airport (SAT)plane plane MSP - SAT
    8h 10m
    $945–1,190

  7. Bus via (7031) 21St St. & Garnett Rd. Eb

    1. Take the bus from La Crosse to Minneapolisbus bus
    2. Take the bus from Minneapolis to Tulsabus bus
    3. Take the bus from Tulsa to San Antoniobus bus
    38h 2m
    $394–482

La Crosse to San Antonio by train (Amtrak)

Calendar10Weekly Trains
Duration38h 44mAverage Duration
Ticket$499Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to San Antonio.ExpandLaunch map view
  • Distance: 1,083.3 mi
  • Duration: 7h 3m

What companies run services between La Crosse, WI, USA and San Antonio, TX, USA?

American Airlines and United Airlines fly from La Crosse (LSE) to San Antonio International Airport (SAT) every 4 hours. Alternatively, you can take a bus from La Crosse to S. St. Mary's & Nueva via Milwaukee, Water & Chicago - Circle K, Dallas, Tornado Bus Co - Dallas I-30, Tornado Bus Co - San Antonio, and I-35 S Access & Yarrow Blvd in around 32h 21m.

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