What is the cheapest way to get from La Crosse to Sioux Falls?

The cheapest way to get from La Crosse to Sioux Falls is to drive which costs $50 - $80 and takes 4h 52m.

What is the fastest way to get from La Crosse to Sioux Falls?

The fastest way to get from La Crosse to Sioux Falls is to drive which takes 4h 52m and costs $50 - $80.

Is there a direct bus between La Crosse and Sioux Falls?

No, there is no direct bus from La Crosse to Sioux Falls. However, there are services departing from La Crosse and arriving at The Bus Stop via Minneapolis and Maple/Career NE corner. The journey, including transfers, takes approximately 11h 58m.

How far is it from La Crosse to Sioux Falls?

The distance between La Crosse and Sioux Falls is 414 miles. The road distance is 298.4 miles.

How do I travel from La Crosse to Sioux Falls without a car?

The best way to get from La Crosse to Sioux Falls without a car is to train and bus via Albert Lea which takes 10h 11m and costs $130 - $230.

How long does it take to get from La Crosse to Sioux Falls?

It takes approximately 10h 11m to get from La Crosse to Sioux Falls, including transfers.

Where do I catch the La Crosse to Sioux Falls bus from?

La Crosse to Sioux Falls bus services, operated by Jefferson Lines, depart from La Crosse station.

Bus or fly from La Crosse to Sioux Falls?

The best way to get from La Crosse to Sioux Falls is to fly which takes 6h 24m and costs $90 - $410. Alternatively, you can bus, which costs $110 - $170 and takes 11h 58m.

Where does the La Crosse to Sioux Falls bus arrive?

La Crosse to Sioux Falls bus services, operated by Jefferson Lines, arrive at Minneapolis station.

Can I drive from La Crosse to Sioux Falls?

Yes, the driving distance between La Crosse to Sioux Falls is 298 miles. It takes approximately 4h 52m to drive from La Crosse to Sioux Falls.

Where can I stay near Sioux Falls?

There are 80+ hotels available in Sioux Falls.

La Crosse to Sioux Falls - 8 ways to travel via train, bus, car, and plane

How to get fromLa Crosse to Sioux Falls

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There are 8 ways to get from La Crosse to Sioux Falls by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train, bus via Albert Lea
best
1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
2. Take the bus from St. Paul to Albert Leabus
3. Take the bus from Albert Lea to Sioux Fallsbus
10h 11m
$130–222
Drive 296.7 mi
cheapest
1. Drive from La Crosse to Sioux Fallscar 296.7 mi
4h 52m
$55–79
Fly from La Crosse
1. Fly from La Crosse (LSE) to Sioux Falls (FSD)plane LSE - FSD
6h 24m
$90–403
Bus
1. Take the bus from La Crosse to Minneapolisbus Jefferson 966 / ...
2. Take the bus from Minneapolis to Sioux Fallsbus Jefferson 701 / ...
11h 58m
$113–166
Train, bus
1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain Empire Builder / ...
2. Take the bus from Minneapolis-St. Paul to Sioux Fallsbus Jefferson Lines 925
13h 24m
$121–200
Train to Minneapolis–Saint Paul International Airport, fly
1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain
2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Sioux Falls (FSD)plane MSP - FSD
6h 53m
$91–420
Bus to Rochester, fly
1. Take the bus from La Crosse to Rochester, MNbus
2. Fly from Rochester (RST) to Sioux Falls (FSD)plane RST - FSD
8h 14m
$76–381
Bus to Dane County Regional Airport-Truax Field, fly
1. Take the bus from La Crosse to UW-Madisonbus
2. Fly from Dane County Regional Airport-Truax Field (MSN) to Sioux Falls (FSD)plane MSN - FSD
9h 42m
$121–522

La Crosse (LSE) to Sioux Falls (FSD) flights

35Weekly Planes

6h 34mAverage Duration

$73Cheapest Price

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Questions & Answers

Map of how to get from La Crosse to Sioux Falls.

Launch map view

Distance: 411.2 mi
Duration: 10h 11m

What companies run services between La Crosse, WI, USA and Sioux Falls, SD, USA?

United Airlines and American Airlines fly from La Crosse (LSE) to Sioux Falls (FSD) 5 times a day. Alternatively, you can take a bus from La Crosse to The Bus Stop via Minneapolis, Sioux Falls, and Maple/Career NE corner in around 11h 58m.

Airlines

Train operators

Bus operators

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