Rome2Rio

How to get fromLa Crosse to South Dakotaby plane, train, bus, or car

Find Transport to South Dakota

See all options

There are 9 ways to get from La Crosse to South Dakota by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly La Crosse to Sioux Falls

    best
    1. Fly from La Crosse (LSE) to Sioux Falls (FSD)plane plane LSE - FSD
    6h 26m
    $90–403

  2. Drive 296.7 mi

    cheapest
    1. Drive from La Crosse to Sioux Fallscar car 296.7 mi
    4h 52m
    $55–79

  3. Train, bus via Fairmont

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Take the bus from Minneapolis to Fairmontbus bus
    3. Take the bus from Fairmont to Sioux Fallsbus bus
    11h 29m
    $131–224

  4. Train to Minneapolis–Saint Paul International Airport, fly to Aberdeen Regional Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Aberdeen Regional Airport (ABR)plane plane MSP - ABR
    6h 1m
    $105–454

  5. Train to Minneapolis–Saint Paul International Airport, fly to Watertown Municipal Airport

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Watertown Municipal Airport (ATY)plane plane MSP - ATY
    5h 53m
    $98–431

  6. Train to Minneapolis–Saint Paul International Airport, fly to Sioux Falls

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Sioux Falls (FSD)plane plane MSP - FSD
    6h 55m
    $90–420

  7. Train to Minneapolis–Saint Paul International Airport, fly to Rapid City

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Rapid City (RAP)plane plane MSP - RAP
    8h 12m
    $124–503

  8. Bus

    1. Take the bus from La Crosse to Minneapolisbus bus Jefferson Lines 966
    2. Take the bus from Minneapolis to Sioux Fallsbus bus Jefferson Lines 701 / ...
    13h 46m
    $115–167

  9. Train, bus

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train Empire Builder / ...
    2. Take the bus from Minneapolis-St. Paul to Sioux Fallsbus bus Jefferson Lines 925
    14h 48m
    $122–202

La Crosse (LSE) to Sioux Falls (FSD) flights

Calendar35Weekly Planes
Duration6h 34mAverage Duration
Ticket$73Cheapest Price
See schedules

Questions & Answers

Map of how to get from La Crosse to South Dakota.ExpandLaunch map view
  • Distance: 286.6 mi
  • Duration: 6h 26m

What companies run services between La Crosse, WI, USA and South Dakota, USA?

United Airlines and American Airlines fly from La Crosse (LSE) to Sioux Falls (FSD) 5 times a day. Alternatively, you can take a bus from La Crosse to 6th/St. Paul NE corner via Minneapolis, Sioux Falls, Maple/Career NE corner, and The Bus Stop in around 13h 46m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers