There are 6 ways to get from La Crosse to Spartanburg by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport
best- Fly from La Crosse (LSE) to Greenville–Spartanburg International Airport (GSP)plane LSE - GSP
5h 47m$193–691Fly to Asheville Regional Airport, drive
cheapest- Fly from La Crosse (LSE) to Asheville Regional Airport (AVL)plane LSE - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
6h 13m$102–436Bus via Milwaukee
- Take the bus from La Crosse to Milwaukeebus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Greenvillebus
27h 31m$260–441Train (Amtrak)
- Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Carytrain
- Take the train from Cary to Charlotte Amtrak Stationtrain
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
36h 58m$503–1,099Drive 953.1 mi
- Drive from La Crosse to Spartanburgcar 953.1 mi
17h 24m$174–252Bus
- Take the bus from La Crosse to Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Servicios Zapata - Spartanburgbus
30h 17m$229–490
La Crosse to Spartanburg by train (Amtrak)
Questions & Answers
The cheapest way to get from La Crosse to Spartanburg is to drive which costs $170 - $260 and takes 17h 24m.
The fastest way to get from La Crosse to Spartanburg is to fly which takes 5h 47m and costs $190 - $700.
No, there is no direct bus from La Crosse to Spartanburg. However, there are services departing from La Crosse and arriving at Greenville via Milwaukee Intermodal Station, Chicago Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 27h 31m.
No, there is no direct train from La Crosse station to Spartanburg station. However, there are services departing from La Crosse Amtrak Station and arriving at Spartanburg Station via Chicago Union Station, Cary and Charlotte Amtrak Station. The journey, including transfers, takes approximately 36h 58m.
The distance between La Crosse and Spartanburg is 816 miles. The road distance is 958.7 miles.
The best way to get from La Crosse to Spartanburg without a car is to bus via Milwaukee which takes 27h 31m and costs $260 - $450.
It takes approximately 5h 47m to get from La Crosse to Spartanburg, including transfers.
La Crosse to Spartanburg bus services, operated by Jefferson Lines, depart from La Crosse station.
La Crosse to Spartanburg train services, operated by Amtrak, depart from La Crosse Amtrak Station.
The best way to get from La Crosse to Spartanburg is to fly which takes 5h 47m and costs $190 - $700. Alternatively, you can bus via Milwaukee, which costs $260 - $450 and takes 27h 31m, you could also train, which costs $500 - $1,100 and takes 36h 58m.
What companies run services between La Crosse, WI, USA and Spartanburg, SC, USA?
American Airlines and United Airlines fly from La Crosse (LSE) to Greenville–Spartanburg International Airport (GSP) 3 times a day. Alternatively, you can take a bus from La Crosse to Spartanburg via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, Atlanta Bus Station, and Greenville in around 27h 31m.
- Website
- aa.com
Flights from La Crosse to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $120–600
Flights from La Crosse to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $75–400
- Website
- united.com
Flights from La Crosse to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $120–600
Flights from La Crosse to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 8h 24m
- When
- Every day
- Estimated price
- $75–400
- Website
- allegiantair.com
Flights from La Crosse to Asheville Regional Airport via Orlando Sanford
- Ave. Duration
- 6h 12m
- When
- Thursday and Sunday
- Estimated price
- $140–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from La Crosse Amtrak Station to Chicago Union Station
- Ave. Duration
- 5h 8m
- Frequency
- 3 times a day
- Estimated price
- $85–190
- Website
- Amtrak
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $340–750
- Website
- Amtrak
Train from Cary to Charlotte Amtrak Station
- Ave. Duration
- 2h 58m
- Frequency
- 5 times a day
- Estimated price
- $50–110
- Website
- Amtrak
Train from Charlotte Amtrak Station to Spartanburg Station
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from La Crosse to Milwaukee
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from La Crosse to Madison
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $13–26
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- Every 4 hours
- Estimated price
- $100–210
- Website
- Greyhound
Bus from Atlanta Bus Station to Greenville
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- Every 4 hours
- Estimated price
- $100–210
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 5 times a day
- Estimated price
- $14–24
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- 3 times a day
- Estimated price
- $110–190
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Greenville
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $23–40
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- 3 times a day
- Estimated price
- $110–190
- Schedules at
- Flixbus USA
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- Rockland Coaches
- Adult
- $26–60
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Servicios Zapata - Spartanburg
- Ave. Duration
- 4h 4m
- Frequency
- Once daily
- Estimated price
- $50–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $50–150
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More Questions & Answers
La Crosse to Spartanburg bus services, operated by Jefferson Lines, arrive at Milwaukee station.
Spartanburg is 1h ahead of La Crosse. It is currently 4:21 AM in La Crosse and 5:21 AM in Spartanburg.
La Crosse to Spartanburg train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between La Crosse to Spartanburg is 959 miles. It takes approximately 17h 24m to drive from La Crosse to Spartanburg.
Book your La Crosse to Spartanburg train tickets online with Omio.
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