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How to get fromLa Crosse to Toledoby train (Amtrak), bus (Amtrak), car, plane, bus, bus (Greyhound, Flixbus), or train

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There are 9 ways to get from La Crosse to Toledo by train (Amtrak), bus (Amtrak), car, plane, bus, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the train from Chicago Union Station to Toledotrain train Floridian / ...
    10h 7m
    $167–343

  2. Drive 520.1 mi

    cheapest
    1. Drive from La Crosse to Toledocar car 520.1 mi
    8h 45m
    $95–138

  3. Bus

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Toledobus bus
    12h 34m
    $153–238

  4. Fly La Crosse to Detroit, bus

    1. Fly from La Crosse (LSE) to Detroit (DTW)plane plane LSE - DTW
    2. Take the bus from Dearborn to Toledobus bus
    7h 33m
    $119–488

  5. Bus via Lake Delton

    1. Take the bus from La Crosse to Wisconsin Dellsbus bus
    2. Take the bus from Wisconsin Dells to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Toledo Bus Stopbus bus
    12h 50m
    $97–184

  6. Fly La Crosse to Chicago O'Hare International Airport, train

    1. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    2. Take the train from Chicago Union Station to Toledotrain train
    7h 33m
    $125–416

  7. Bus to Dane County Regional Airport-Truax Field, fly to Detroit, bus

    1. Take the bus from La Crosse to UW-Madisonbus bus
    2. Fly from Dane County Regional Airport-Truax Field (MSN) to Detroit (DTW)plane plane MSN - DTW
    3. Take the bus from Dearborn to Toledobus bus
    9h 42m
    $155–647

  8. Train to Minneapolis–Saint Paul International Airport, fly to Detroit, bus

    1. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    3. Take the bus from Dearborn to Toledobus bus
    9h 35m
    $540–1,324

  9. Bus to Appleton International Airport, fly to Detroit, bus

    1. Take the bus from La Crosse Grand River Station to Appleton Valley Transitbus bus
    2. Fly from Appleton International Airport (ATW) to Detroit (DTW)plane plane ATW - DTW
    3. Take the bus from Dearborn to Toledobus bus
    10h 11m
    $136–484

La Crosse to Toledo by train (Amtrak)

Calendar21Weekly Trains
Duration10h 7mAverage Duration
Ticket$167Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Toledo.ExpandLaunch map view
  • Distance: 512.5 mi
  • Duration: 10h 7m

What companies run services between La Crosse, WI, USA and Toledo, OH, USA?

You can take a train from La Crosse Amtrak Station to Toledo via Chicago Union Station in around 10h 7m. Alternatively, you can take a bus from La Crosse to Toledo via 250 N. Lake St - Madison UW Campus, W Jackson Blvd, after S Clinton St, and Chicago Union Station in around 12h 34m.

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