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How to get fromLa Crosse to Waterlooby bus, shuttle, car, train, or bus (Greyhound)

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There are 4 ways to get from La Crosse to Waterloo by bus, shuttle, car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, shuttle

    best
    1. Take the bus from La Crosse to Rochester, MNbus bus
    2. Take a shuttle bus from Rochester Sinclair to Owatonna, MNshuttle bus
    3. Take the bus from Owatonna to Des Moinesbus bus
    4. Take the bus from Des Moines to Waterloobus bus
    12h 15m
    $101–184

  2. Drive 132.4 mi

    cheapest
    1. Drive from La Crosse to Waterloocar car 132.4 mi
    2h 49m
    $25–35

  3. Train, bus

    1. Take the train from La Crosse Amtrak Station to Chicago Union Stationtrain train Empire Builder / ...
    2. Take the bus from Chicago Bus Station to Waterloobus bus Greyhound US0154S
    13h 12m
    $140–284

  4. Bus

    1. Take the bus from La Crosse to St. Paulbus bus
    2. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    3. Take the bus from Des Moines to Waterloobus bus
    13h 35m
    $97–166

La Crosse to Waterloo by train, foot, and bus

Calendar5Weekly Services
Duration13h 12mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from La Crosse to Waterloo.ExpandLaunch map view
  • Distance: 425.2 mi
  • Duration: 12h 15m

What companies run services between La Crosse, WI, USA and Waterloo, IA, USA?

You can take a bus from La Crosse to Waterloo via St. Paul, Saint Paul Union Depot, and Des Moines in around 13h 35m.

Train operators
Bus operators

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