Rome2Rio

How to get fromLa Grange to Knoxvilleby bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

Find Transport to Knoxville

See all options

There are 9 ways to get from La Grange to Knoxville by bus, plane, bus (Flixbus), train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 330 bus to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from La Grange/47th to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    3h 57m
    $169–728

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h
    $86–383

  3. Bus

    1. Take the bus from Chicago Bus Station to New York Midtownbus bus FlixBus N2641 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    33h 39m
    $321–482

  4. Train, bus

    1. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train Lake Shore Limited / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    35h 48m
    $479–910

  5. Drive 529.3 mi

    1. Drive from La Grange to Knoxvillecar car 529.3 mi
    9h 18m
    $97–140

  6. Line 330 bus to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from La Grange/47th to Archer/Harlembus bus
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    3h 58m
    $190–876

  7. Fly Chicago O'Hare International Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    5h 26m
    $132–686

  8. Train, bus via Ossining

    1. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    2. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    35h 57m
    $432–785

  9. Bus via Baltimore

    1. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    37h 1m
    $342–598

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar74Weekly Planes
Duration2h 46mAverage Duration
Ticket$109Cheapest Price
See schedules

Questions & Answers

Map of how to get from La Grange to Knoxville.ExpandLaunch map view
  • Distance: 504.9 mi
  • Duration: 3h 57m

What companies run services between La Grange, Cook County, IL, USA and Knoxville, TN, USA?

You can take a bus from La Grange/47th to Knoxville via Archer/Harlem, Archer & Neva Terminal, Dearborn & Jackson, Adams & Wabash, Harrison & Jefferson, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 33h 39m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers