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How to get fromLa Jolla to Santa Claraby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 7 ways to get from La Jolla to Santa Clara by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 30 bus, fly to Norman Y. Mineta San José International Airport

    best
    1. Take the bus from Silverado St & Herschel Av to Old Town Transit Centerbus bus
    2. Fly from San Diego International Airport (SAN) to Norman Y. Mineta San José International Airport (SJC)plane plane SAN - SJC
    3h 47m
    $76–488

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from San Diego Greyhound Bus Stop to San Jose Diridon Stationbus bus Greyhound US0831
    11h 46m
    $70–151

  3. Train (Amtrak)

    1. Take the train from San Diego Old Town Transportation Center to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    15h 33m
    $170–376

  4. Drive 454.2 mi

    1. Drive from La Jolla to Santa Claracar car 454.2 mi
    7h 49m
    $83–120

  5. Fly to San Francisco International Airport, Caltrain

    1. Fly from San Diego International Airport (SAN) to San Francisco International Airport (SFO)plane plane SAN - SFO
    2. Take the train from Millbrae Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    4h 49m
    $78–255

  6. Fly to Oakland International Airport, train

    1. Fly from San Diego International Airport (SAN) to Oakland International Airport (OAK)plane plane SAN - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    5h 35m
    $76–303

  7. Bus via Tijuana

    1. Take the bus from San Ysidro to San Jose - King Rdbus bus San Ysidro
    14h
    $96–142

La Jolla to Santa Clara by bus and train (Greyhound)

Calendar7Weekly Services
Duration11h 46mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from La Jolla to Santa Clara.ExpandLaunch map view
  • Distance: 436.5 mi
  • Duration: 3h 47m

What companies run services between La Jolla, San Diego County, CA, USA and Santa Clara, CA, USA?

Greyhound USA operates a bus from San Diego Greyhound Bus Stop to San Jose Diridon Station once daily. Tickets cost $65–140 and the journey takes 9h 50m. Alternatively, you can take a bus from Silverado St & Herschel Av to Santa Clara Caltrain Northbound via Old Town Transit Center, San Diego Old Town Transportation Center, Los Angeles, San Jose, and San Jose Diridon Caltrain Northbound in around 15h 33m.

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