There are 6 ways to get from La Mesa to Amarillo by plane, bus (Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from San Diego International Airport
best- Fly from San Diego International Airport (SAN) to Rick Husband Amarillo International Airport (AMA)plane SAN - AMA
6h 42m$116–473Bus
- Take the bus from El Cajon Transit Center to Phoenix Bus Stationbus Greyhound US0851S
- Take the bus from Phoenix Bus Station to Amarillo Multimodal Transfer Stabus Greyhound US1210
23h 36m$177–337Train, bus
- Take the train from San Diego Old Town Transportation Center to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to Albuquerque Alvarado Transportation Centertrain
- Take the bus from Albuquerque Bus Station to Amarillo Multimodal Transfer Stabus
26h 35m$357–769Drive 1,037.6 mi
- Drive from La Mesa to Amarillocar 1,037.6 mi
17h 8m$190–274Fly from Mcclellan–Palomar Airport
- Fly from Mcclellan–Palomar Airport (CLD) to Rick Husband Amarillo International Airport (AMA)plane CLD - AMA
11h 26m$141–558Bus via Ciudad Juárez
- Take the bus from Cross Border Express, San Diego to El Pasobus Cbx
- Take the bus from El Paso to Amarillobus OK City / ...
27h 26m$251–355
La Mesa to Amarillo by tram and bus
Questions & Answers
The cheapest way to get from La Mesa to Amarillo is to bus which costs $170 - $340 and takes 23h 36m.
The fastest way to get from La Mesa to Amarillo is to fly which takes 6h 42m and costs $110 - $480.
No, there is no direct bus from La Mesa to Amarillo. However, there are services departing from El Cajon Transit Center and arriving at Amarillo Multimodal Transfer Sta via Phoenix Bus Station. The journey, including transfers, takes approximately 23h 36m.
The distance between La Mesa and Amarillo is 935 miles. The road distance is 1043.6 miles.
The best way to get from La Mesa to Amarillo without a car is to bus which takes 23h 36m and costs $170 - $340.
It takes approximately 6h 42m to get from La Mesa to Amarillo, including transfers.
La Mesa to Amarillo bus services, operated by Greyhound USA, depart from El Cajon Transit Center station.
The best way to get from La Mesa to Amarillo is to fly which takes 6h 42m and costs $110 - $480. Alternatively, you can bus, which costs $170 - $340 and takes 23h 36m.
La Mesa to Amarillo bus services, operated by Greyhound USA, arrive at Phoenix Bus Station.
Amarillo is 2h ahead of La Mesa. It is currently 7:58 AM in La Mesa and 9:58 AM in Amarillo.
What companies run services between La Mesa, CA, USA and Amarillo, TX, USA?
Southwest Airlines, American Airlines, and United Airlines fly from San Diego International Airport (SAN) to Rick Husband Amarillo International Airport (AMA) every 4 hours. Alternatively, you can take a vehicle from La Mesa Blvd Station to Amarillo Multimodal Transfer Sta via El Cajon Station, El Cajon Transit Center, and Phoenix Bus Station in around 23h 36m.
- Website
- southwest.com
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Las Vegas
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $90–430
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Dallas
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $120–550
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Austin
- Ave. Duration
- 5h 10m
- When
- Sunday
- Estimated price
- $130–550
- Website
- united.com
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Denver
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $100–470
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Houston
- Ave. Duration
- 8h 29m
- When
- Every day
- Estimated price
- $140–600
Flights from Mcclellan–Palomar Airport to Rick Husband Amarillo International Airport via Denver
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $110–490
- Website
- aa.com
Flights from San Diego International Airport to Rick Husband Amarillo International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego Old Town Transportation Center to Fullerton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to Albuquerque Alvarado Transportation Center
- Ave. Duration
- 15h 57m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from El Cajon Transit Center to Phoenix Bus Station
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Bus from Phoenix Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 14h 25m
- Frequency
- Twice daily
- Estimated price
- $120–230
- Website
- https://www.greyhound.com/
Bus from Albuquerque Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from El Cajon Transit Center to Phoenix Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a week
- Schedules at
- greyhound.com
Bus from Phoenix Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 14h 25m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Albuquerque Bus Station to Amarillo Multimodal Transfer Sta
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
- [email protected]
- Website
- crossborderxpress.com
Bus from Cross Border Express, San Diego to El Paso
- Ave. Duration
- 17h
- Frequency
- 3 times a day
- Estimated price
- $120–170
- Schedules at
- crossborderxpress.com
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from El Paso to Amarillo
- Ave. Duration
- 5h 41m
- Frequency
- Twice daily
- Estimated price
- $80–110
- Schedules at
- omnibusexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between La Mesa to Amarillo is 1044 miles. It takes approximately 17h 8m to drive from La Mesa to Amarillo.
There are 184+ hotels available in Amarillo.










