There are 4 ways to get from La Mesa to Irvine by tram, train, bus (Greyhound), car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Tram, train
best- Take the tram from 70th Street Station to Old Town Stationtram Green
- Take the train from San Diego Old Town Transportation Center to Irvinetrain Pacific Surfliner
3h 59m$33–78Drive 89 mi
cheapest- Drive from La Mesa to Irvinecar 89 mi
1h 33m$17–24Bus, line 53 bus
- Take the bus from San Diego to Anaheimbus Tijuana
- Take the bus from Artic - Dock 4 to Main-Paseo Westparkbus 53
4h 55m$23–45Line 215 bus, bus
- Take the bus from SDSU Transit Center to India St & C Stbus 215
- Take the bus from San Diego to Irvinebus Amtrak Thruway Connecting Service
4h 56m$32–47
La Mesa to Irvine by tram and train
Questions & Answers
The cheapest way to get from La Mesa to Irvine is to drive which costs $16 - $24 and takes 1h 33m.
The fastest way to get from La Mesa to Irvine is to drive which takes 1h 33m and costs $16 - $24.
No, there is no direct bus from La Mesa to Irvine. However, there are services departing from San Diego and arriving at Main-Paseo Westpark via Artic - Dock 4. The journey, including transfers, takes approximately 4h 55m.
No, there is no direct train from La Mesa station to Irvine. However, there are services departing from 70th Street Station and arriving at Tustin via San Diego Old Town Transportation Center and Irvine. The journey, including transfers, takes approximately 3h 59m.
The distance between La Mesa and Irvine is 96 miles. The road distance is 89.5 miles.
The best way to get from La Mesa to Irvine without a car is to tram and train which takes 3h 59m and costs $30 - $80.
It takes approximately 3h 59m to get from La Mesa to Irvine, including transfers.
La Mesa to Irvine bus services, operated by Greyhound Mexico, depart from San Diego station.
La Mesa to Irvine train services, operated by San Diego Metro Transit, depart from 70th Street Station.
La Mesa to Irvine bus services, operated by Greyhound Mexico, arrive at Anaheim station.
What companies run services between La Mesa, CA, USA and Irvine, CA, USA?
You can take a vehicle from La Mesa Blvd Station to Main-Paseo Westpark via 12th & Imperial Station, San Diego, Anaheim, and Artic - Dock 4 in around 4h 55m.
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Tram from 70th Street Station to Old Town Station
- Ave. Duration
- 28 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–14
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego Old Town Transportation Center to Irvine
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from San Diego to Anaheim
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $19–30
- Schedules at
- greyhound.com.mx
- Phone
- +1 714-560-6282
- Website
- octa.net
Bus from Artic - Dock 4 to Main-Paseo Westpark
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- octa.net
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Bus from SDSU Transit Center to India St & C St
- Ave. Duration
- 49 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–5
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- One Way - Adult/Youth
- $2–5
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from San Diego to Irvine
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $28–40
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
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More Questions & Answers
La Mesa to Irvine train services, operated by San Diego Metro Transit, arrive at Old Town Station.
Yes, the driving distance between La Mesa to Irvine is 90 miles. It takes approximately 1h 33m to drive from La Mesa to Irvine.
There are 1536+ hotels available in Irvine.













