There are 4 ways to get from La Mesa to Palm Desert by bus (Greyhound, Flixbus), car, train, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via El Centro
best- Take the bus from El Cajon Transit Center to El Centro Bus Stopbus Greyhound US0851S
- Take the bus from El Centro Bus Stop to Indio Bus Stationbus Greyhound US0850
6h 52m$28–55Bus
cheapest- Take the bus from San Diego to San Bernardino Downtown Transit Centerbus FlixBus 2015 / ...
- Take the bus from San Bernardino Transit Center to Varner at Harry Oliverbus 10
8h 18m$21–45Drive 120 mi
- Drive from La Mesa to Palm Desertcar 120 mi
2h 21m$22–32Train, bus (Amtrak)
- Take the train from San Diego Old Town Transportation Center to Fullerton Amtrak Stationtrain Pacific Surfliner
- Take the bus from Fullerton Amtrak Station to Palm Desert Amtrak Bus Stopbus Amtrak Thruway Connecting Service
7h 13m$67–129
La Mesa to Palm Desert by tram, bus, and foot
Questions & Answers
The cheapest way to get from La Mesa to Palm Desert is to drive which costs $21 - $35 and takes 2h 21m.
The fastest way to get from La Mesa to Palm Desert is to drive which takes 2h 21m and costs $21 - $35.
No, there is no direct bus from La Mesa to Palm Desert. However, there are services departing from El Cajon Transit Center and arriving at Hwy 111 at San Luis Rey via El Centro Bus Stop and Hwy 111 at Golf Center Pkwy. The journey, including transfers, takes approximately 6h 52m.
The distance between La Mesa and Palm Desert is 202 miles. The road distance is 120.7 miles.
The best way to get from La Mesa to Palm Desert without a car is to bus via El Centro which takes 6h 52m and costs $28 - $55.
It takes approximately 6h 52m to get from La Mesa to Palm Desert, including transfers.
La Mesa to Palm Desert bus services, operated by Greyhound USA, depart from El Cajon Transit Center station.
La Mesa to Palm Desert bus services, operated by Greyhound USA, arrive at El Centro Bus Stop station.
Yes, the driving distance between La Mesa to Palm Desert is 121 miles. It takes approximately 2h 21m to drive from La Mesa to Palm Desert.
There are 1793+ hotels available in Palm Desert.
What companies run services between La Mesa, CA, USA and Palm Desert, CA, USA?
You can take a vehicle from La Mesa Blvd Station to Hwy 111 at San Luis Rey via El Cajon Station, El Cajon Transit Center, El Centro Bus Stop, Indio Bus Station, and Hwy 111 at Golf Center Pkwy in around 6h 52m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego Old Town Transportation Center to Fullerton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from El Cajon Transit Center to El Centro Bus Stop
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $15–29
- Website
- Greyhound
Bus from El Centro Bus Stop to Indio Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $12–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from El Centro Bus Stop to Indio Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $13–23
- Schedules at
- Flixbus USA
Bus from San Diego to San Bernardino Downtown Transit Center
- Ave. Duration
- 2h 50m
- Frequency
- 4 times a day
- Estimated price
- $17–29
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Fullerton Amtrak Station to Palm Desert Amtrak Bus Stop
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $35–50
- Website
- Amtrak
- Phone
- +1 760-343-3451
- Website
- Sunline Transit
Bus from San Bernardino Transit Center to Varner at Harry Oliver
- Ave. Duration
- 1h 50m
- Frequency
- 3 times a day
- Estimated price
- $1
- Schedules at
- Sunline Transit
- Seniors 60+, Disabled, Medicare
- $1
- Youth 5-17
- $1
- Adults 18-59
- $1
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