Rome2Rio

How to get fromLa Mesa to Santa Anaby tram, train, bus, car, or bus (Greyhound)

Find Transport to Santa Ana

See all options

There are 4 ways to get from La Mesa to Santa Ana by tram, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Tram, train

    best
    1. Take the tram from 70th Street Station to Old Town Stationtram tram Green
    2. Take the train from San Diego Old Town Transportation Center to Santa Anatrain train Pacific Surfliner
    3h 15m
    $31–74

  2. Line 10 bus, bus

    cheapest
    1. Take the bus from University Av & College Av to Old Town Transit Centerbus bus 10
    2. Take the bus from San Diego Greyhound Bus Stop to Santa Ana Bus Stopbus bus Greyhound US0831
    3h 27m
    $16–31

  3. Tram, bus

    1. Take the tram from La Mesa Blvd Station to 12th & Imperial Stationtram tram Orange
    2. Take the bus from San Diego to Santa Anabus bus Tijuana
    3h 25m
    $20–41

  4. Drive 92 mi

    1. Drive from La Mesa to Santa Anacar car 92 mi
    1h 37m
    $17–25

La Mesa to Santa Ana by tram and train

Calendar91Weekly Services
Duration3h 15mAverage Duration
Ticket$31Cheapest Price
See schedules

Questions & Answers

Map of how to get from La Mesa to Santa Ana.ExpandLaunch map view
  • Distance: 99.7 mi
  • Duration: 3h 15m

What companies run services between La Mesa, CA, USA and Santa Ana, CA, USA?

You can take a bus from University Av & College Av to Santa Ana Bus Stop via Old Town Transit Center and San Diego Greyhound Bus Stop in around 3h 27m.

Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers