There are 4 ways to get from La Mesa to Simi Valley by train (Amtrak), tram, bus, subway, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from San Diego Old Town Transportation Center to Moorpark Amtraktrain Pacific Surfliner
6h 59m$58–138Tram, bus, subway, line 10 bus
cheapest- Take the tram from La Mesa Blvd Station to 12th & Imperial Stationtram
- Take the bus from San Diego to Los Angeles Union Stationbus
- Take the subway from Union Station - Metro B & D Lines to North Hollywood Stationsubway
- Take the bus from North Hollywood Station to Chatsworth Stationbus
- Take the bus from Metrolink Chatsworth to Cochran Street and First Streetbus 10
8h 8m$28–59Drive 164.4 mi
- Drive from La Mesa to Simi Valleycar 164.4 mi
2h 53m$30–44Line 10 bus, bus, line 237 bus
- Take the bus from University Av & College Av to Old Town Transit Centerbus 10
- Take the bus from San Diego to LAX Terminal 3 Shared Rides Stopbus
- Take the bus from LAX Tom Bradley International Terminal to Van Nuys FlyAway Terminal - 7610 Woodley Avebus Lax
- Take the bus from Woodley / Saticoy to Chandler / Lankershimbus 237
- Take the bus from North Hollywood Station to Chatsworth Stationbus
- Take the bus from Metrolink Chatsworth to Cochran Street and First Streetbus 10
10h 2m$66–134
La Mesa to Simi Valley by tram, train, and bus (Amtrak)
Questions & Answers
The cheapest way to get from La Mesa to Simi Valley is to drive which costs $30 - $45 and takes 2h 53m.
The fastest way to get from La Mesa to Simi Valley is to drive which takes 2h 53m and costs $30 - $45.
No, there is no direct bus from La Mesa to Simi Valley. However, there are services departing from University Av & College Av and arriving at Cochran Street and First Street via San Diego, LAX Tom Bradley International Terminal, Woodley / Saticoy, North Hollywood Station and Metrolink Chatsworth. The journey, including transfers, takes approximately 10h 2m.
No, there is no direct train from La Mesa station to Simi Valley. However, there are services departing from 70th Street Station and arriving at Moorpark Amtrak via San Diego Old Town Transportation Center. The journey, including transfers, takes approximately 6h 59m.
The distance between La Mesa and Simi Valley is 191 miles. The road distance is 165.3 miles.
The best way to get from La Mesa to Simi Valley without a car is to train which takes 6h 59m and costs $55 - $140.
It takes approximately 6h 59m to get from La Mesa to Simi Valley, including transfers.
La Mesa to Simi Valley bus services, operated by San Diego Metro Transit, depart from University Av & College Av station.
La Mesa to Simi Valley train services, operated by Amtrak, depart from San Diego Old Town Transportation Center station.
The best way to get from La Mesa to Simi Valley is to train which takes 6h 59m and costs $55 - $140. Alternatively, you can line 10 bus and bus and line 237 bus, which costs $65 - $140 and takes 10h 2m.
What companies run services between La Mesa, CA, USA and Simi Valley, CA, USA?
Amtrak operates a train from San Diego Old Town Transportation Center to Moorpark Amtrak 5 times a day. Tickets cost $55–120 and the journey takes 4h 14m. Alternatively, you can take a bus from University Av & College Av to Cochran Street and First Street via Old Town Transit Center, San Diego, LAX Terminal 3 Shared Rides Stop, LAX Tom Bradley International Terminal, Van Nuys FlyAway Terminal - 7610 Woodley Ave, Woodley / Saticoy, Chandler / Lankershim, North Hollywood Station, Chatsworth Station, and Metrolink Chatsworth in around 10h 2m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego Old Town Transportation Center to Moorpark Amtrak
- Ave. Duration
- 4h 14m
- Frequency
- 5 times a day
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Tram from La Mesa Blvd Station to 12th & Imperial Station
- Ave. Duration
- 30 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–14
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- Phone
- +1-323-466-3876
- [email protected]
- Website
- metro.net
Subway from Union Station - Metro B & D Lines to North Hollywood Station
- Ave. Duration
- 32 min
- Frequency
- Every 15 minutes
- Estimated price
- $2
- Website
- https://www.metro.net
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $23–40
- Schedules at
- greyhound.com.mx
- Phone
- +1-323-466-3876
- [email protected]
- Website
- metro.net
Bus from North Hollywood Station to Chatsworth Station
- Ave. Duration
- 59 min
- Frequency
- Every 15 minutes
- Estimated price
- $1–2
- Website
- https://www.metro.net
Bus from Woodley / Saticoy to Chandler / Lankershim
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $1–2
- Website
- https://www.metro.net
Bus from North Hollywood Station to Chatsworth Station
- Ave. Duration
- 59 min
- Frequency
- Every 15 minutes
- Estimated price
- $1–2
- Website
- https://www.metro.net
- Phone
- +1 (805) 583-6456
- Website
- simivalley.org
Bus from Metrolink Chatsworth to Cochran Street and First Street
- Ave. Duration
- 58 min
- Frequency
- Every 3 hours
- Estimated price
- $2
- Website
- https://www.simivalley.org/departments/public-works/simi-valley-transit
- Youth and College students with student ID
- $0
- Adults
- $2
Bus from Metrolink Chatsworth to Cochran Street and First Street
- Ave. Duration
- 58 min
- Frequency
- Every 3 hours
- Estimated price
- $2
- Website
- https://www.simivalley.org/departments/public-works/simi-valley-transit
- Youth and College students with student ID
- $0
- Adults
- $2
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Bus from University Av & College Av to Old Town Transit Center
- Ave. Duration
- 52 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–5
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- One Way - Adult/Youth
- $2–5
- Phone
- (858) 430-8440
- [email protected]
- Website
- gorelaxsan.com
Bus from San Diego to LAX Terminal 3 Shared Rides Stop
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Website
- https://www.gorelaxsan.com/
- Phone
- (323)-776-5467
- [email protected]
- Website
- laxlinq.com
Bus from San Diego to LAX Terminal 3 Shared Rides Stop
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://laxlinq.com/
- Phone
- (855) 463-5252
- [email protected]
- Website
- flylax.com
Bus from LAX Tom Bradley International Terminal to Van Nuys FlyAway Terminal - 7610 Woodley Ave
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $7–13
- Website
- https://www.flylax.com/flyaway-bus
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More Questions & Answers
La Mesa to Simi Valley bus services, operated by San Diego Metro Transit, arrive at Old Town Transit Center station.
La Mesa to Simi Valley train services, operated by Amtrak, arrive at Moorpark Amtrak station.
Yes, the driving distance between La Mesa to Simi Valley is 165 miles. It takes approximately 2h 53m to drive from La Mesa to Simi Valley.
There are 175+ hotels available in Simi Valley.




















