Rome2Rio

How to get fromLa Mesa to Tucsonby tram, plane, bus, train, bus (Greyhound, Flixbus), car, or train (Amtrak)

Find Transport to Tucson

See all options

There are 7 ways to get from La Mesa to Tucson by tram, plane, bus, train, bus (Greyhound, Flixbus), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Tram, fly to Tucson

    best
    1. Take the tram from La Mesa Blvd Station to Civic Center Stationtram tram
    2. Fly from San Diego International Airport (SAN) to Tucson (TUS)plane plane SAN - TUS
    4h 24m
    $444–770

  2. Drive  399.2 mi

    cheapest
    1. Drive from La Mesa to Tucsoncar car 399.2 mi
    6h 19m
    $73–106

  3. Bus, train

    1. Take the bus from El Cajon Transit Center to Yuma County Area Transitbus bus Greyhound US0851S
    2. Take the train from Yuma Amtrak to Tucson Amtrak Stationtrain train Texas Eagle / ...
    11h 38m
    $161–266

  4. Bus via Phoenix

    1. Take the bus from El Cajon Transit Center to Phoenix Bus Stationbus bus Greyhound US0851S
    2. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Tucson Downtownbus bus FlixBus 2042 / ...
    11h 58m
    $80–118

  5. Fly to Phoenix, bus

    1. Fly from San Diego International Airport (SAN) to Phoenix (PHX)plane plane SAN - PHX
    2. Take the bus from Sky Harbor International Airport to University of Phoenixbus bus
    6h 3m
    $124–345

  6. Train (Amtrak)

    1. Take the train from San Diego Old Town Transportation Center to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Tucson Amtrak Stationtrain train Texas Eagle / ...
    14h 48m
    $337–554

  7. Bus

    1. Take the bus from Cross Border Express, San Diego to Tucsonbus bus Cbx
    18h 27m
    $87–143

La Mesa to Tucson by tram, bus, and train

Calendar6Weekly Services
Duration11h 38mAverage Duration
Ticket$161Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from La Mesa to Tucson.ExpandLaunch map view
  • Distance: 392.3 mi
  • Duration: 4h 24m

What companies run services between La Mesa, CA, USA and Tucson, AZ, USA?

You can take a vehicle from La Mesa Blvd Station to Broadway/Country Club via El Cajon Station, El Cajon Transit Center, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Tucson Downtown, and Downtown Ronstadt Center in around 11h 58m. Alternatively, you can take a vehicle from 70th Street Station to Tucson Amtrak Station via Old Town Station, San Diego Old Town Transportation Center, and Los Angeles in around 14h 48m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There