There are 4 ways to get from La Paz to Santa Cruz by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from El Alto International Airport (LPB) to Comodoro Arturo Merino Benítez International Airport (SCL)plane LPB - SCL
- Take the bus from Terminal Sur de Santiago to Santa Cruzbus
8h 49m$217–515Bus via Arica
cheapest- Take the bus from La Paz to Aricabus
- Take the bus from Terminal Rodoviario de Arica to Terminal San Borjabus
- Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus
44h 47m$86–175Bus
- Take the bus from La Paz to Orurobus
- Take the bus from Oruro to Terminal Alameda - Turbusbus
- Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus
41h 9mDrive 2,491.6 km
- Drive from La Paz to Santa Cruzcar 2,491.6 km
32h 51m$308–444
El Alto International Airport (LPB) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Questions & Answers
The cheapest way to get from La Paz to Santa Cruz is to bus via Arica which costs $85 - $180 and takes 44h 47m.
The fastest way to get from La Paz to Santa Cruz is to fly and bus which takes 8h 49m and costs $210 - $550.
No, there is no direct bus from La Paz to Santa Cruz. However, there are services departing from La Paz and arriving at Terminal de Buses Santa Cruz via Oruro and Terminal Sur de Santiago. The journey, including transfers, takes approximately 41h 9m.
The distance between La Paz and Santa Cruz is 2109 km. The road distance is 2491.6 km.
The best way to get from La Paz to Santa Cruz without a car is to bus which takes 41h 9m and costs .
It takes approximately 8h 49m to get from La Paz to Santa Cruz, including transfers.
La Paz to Santa Cruz bus services, operated by Asociacion Illimani de Transportes, depart from La Paz station.
La Paz to Santa Cruz bus services, operated by Asociacion Illimani de Transportes, arrive at Oruro station.
Yes, the driving distance between La Paz to Santa Cruz is 2492 km. It takes approximately 32h 51m to drive from La Paz to Santa Cruz.
There are 81+ hotels available in Santa Cruz.
What companies run services between La Paz, Bolivia and Santa Cruz, O'Higgins, Chile?
You can take a bus from La Paz to Terminal de Buses Santa Cruz via Oruro, Terminal Alameda - Turbus, and Terminal Sur de Santiago in around 41h 9m.
- Website
- latam.com
Flights from El Alto International Airport to Comodoro Arturo Merino Benítez International Airport via Lima
- Ave. Duration
- 8h 45m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–450
Flights from El Alto International Airport to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 5h 44m
- When
- Thursday, Saturday, and Wednesday
- Estimated price
- $200–450
Flights from El Alto International Airport to Comodoro Arturo Merino Benítez International Airport via Cochabamba, Santa Cruz
- Ave. Duration
- 6h 5m
- When
- Wednesday
- Estimated price
- $200–450
- Website
- boa.bo
Flights from El Alto International Airport to Comodoro Arturo Merino Benítez International Airport via Santa Cruz
- Ave. Duration
- 8h 40m
- When
- Tuesday and Friday
- Estimated price
- $190–440
Flights from El Alto International Airport to Comodoro Arturo Merino Benítez International Airport via Cochabamba, Santa Cruz
- Ave. Duration
- 6h 25m
- When
- Tuesday and Friday
- Estimated price
- $190–440
- Website
- Flixbus Chile
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $19–35
- Schedules at
- Flixbus Chile
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $14–35
Bus from Terminal Rodoviario de Arica to Terminal San Borja
- Ave. Duration
- 29h 30m
- Frequency
- Twice daily
- Estimated price
- $60–85
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $60–85
- Phone
- +591 7750 0534
- [email protected]
- Website
- Asociacion Illimani de Transportes
Bus from La Paz to Oruro
- Ave. Duration
- 4h
- Frequency
- Once daily
- Website
- Asociacion Illimani de Transportes
- Phone
- +591 2527 7355
- [email protected]
- Website
- Jet Nort Super Class
Bus from Oruro to Terminal Alameda - Turbus
- Ave. Duration
- 33h 3m
- Frequency
- 4 times a week
- Estimated price
- $44
- Schedules at
- Jet Nort Super Class
- [email protected]
- Website
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $8
- Schedules at
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $8
- Schedules at
- Expreso Santa Cruz
- Phone
- +56 22 683 8528
- [email protected]
- Website
- Andimar
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–9
- Cama
- $5–11
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–9
- Cama
- $5–11
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
- Phone
- +56 2 2666 5505
- [email protected]
- Website
- Buses Jetsur
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 13m
- Frequency
- 4 times a day
- Estimated price
- $10–13
- Website
- Buses Jetsur
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 13m
- Frequency
- 4 times a day
- Estimated price
- $10–13
- Website
- Buses Jetsur
- Phone
- +56 6063 9308
- Website
- Pullman Bus Santiagonor
Bus from La Paz to Arica
- Ave. Duration
- 10h 30m
- Frequency
- 3 times a day
- Estimated price
- $22
- Schedules at
- Pullman Bus Santiagonor
- [email protected]
- Website
- Pullman San Andres
Bus from Terminal Rodoviario de Arica to Terminal San Borja
- Ave. Duration
- 30h
- Frequency
- Every 4 hours
- Estimated price
- $77–140
- Schedules at
- Pullman San Andres
- Semi Cama
- $90–130
- Cama
- $100–140
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