What is the cheapest way to get from La Salle to Des Moines?

The cheapest way to get from La Salle to Des Moines is to drive which costs $45 - $70 and takes 4h 11m.

What is the fastest way to get from La Salle to Des Moines?

The fastest way to get from La Salle to Des Moines is to drive which takes 4h 11m and costs $45 - $70.

How far is it from La Salle to Des Moines?

The distance between La Salle and Des Moines is 304 miles. The road distance is 251.4 miles.

How do I travel from La Salle to Des Moines without a car?

The best way to get from La Salle to Des Moines without a car is to train and bus which takes 7h 32m and costs $100 - $180.

How long does it take to get from La Salle to Des Moines?

It takes approximately 7h 32m to get from La Salle to Des Moines, including transfers.

Can I drive from La Salle to Des Moines?

Yes, the driving distance between La Salle to Des Moines is 251 miles. It takes approximately 4h 11m to drive from La Salle to Des Moines.

Where can I stay near Des Moines?

There are 238+ hotels available in Des Moines.

La Salle to Des Moines - 4 ways to travel via train, bus, car, and plane

How to get fromLa Salle to Des Moines

Travel from

See all options

Search accommodation with Expedia

There are 4 ways to get from La Salle to Des Moines by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train, bus
best
1. Take the train from Mendota Station to Galesburg Amtrak Stationtrain Southwest Chief / ...
2. Take the bus from Galesburg to Des Moinesbus Greyhound US0157S
7h 32m
$104–174
Drive 250 mi
cheapest
1. Drive from La Salle to Des Moinescar 250 mi
4h 11m
$46–66
Train to Chicago O'Hare International Airport, fly
1. Take the train from Mendota Station to La Grange Amtraktrain
2. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
5h 37m
$167–623
Train to Chicago Midway International Airport, fly
1. Take the train from Mendota Station to Chicago Union Stationtrain
2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
5h 49m
$187–743

Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights

63Weekly Planes

1h 30mAverage Duration

$75Cheapest Price

See schedules

Questions & Answers

Map of how to get from La Salle to Des Moines.

Launch map view

Distance: 302.2 mi
Duration: 7h 32m

What companies run services between La Salle, IL, USA and Des Moines, IA, USA?

There is no direct connection from La Salle to Des Moines. However, you can take the taxi to Mendota Station, take the train to Galesburg Amtrak Station, walk to Galesburg, then take the bus to Des Moines. Alternatively, you can drive from La Salle to Des Moines in around 4h 11m.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.