There are 6 ways to get from La Serena to Antofagasta Region by plane, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Antofagasta Airport
best- Fly from La Florida Airport (LSC) to Antofagasta Airport (ANF)plane LSC - ANF
1h 18m$40–170Bus #2
cheapest- Take the bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavadabus Calama / ...
12h 4m$21–77Bus via Antofagasta
- Take the bus from Terminal de buses La Serena to Antofagastabus Calama
11h 12m$25–44Drive 845.4 km
- Drive from La Serena to Antofagastacar 845.4 km
10h 48m$105–151Fly to Calama Airport
- Fly from La Florida Airport (LSC) to Calama Airport (CJC)plane LSC - CJC
2h 16m$57–229Bus
- Take the bus from Terminal de buses La Serena to Antofagastabus FlixBus CL071 / ...
11h 53m$37–45
La Serena to Antofagasta Region by bus
Questions & Answers
The cheapest way to get from La Serena to Antofagasta Region is to bus via Antofagasta which costs $25 - $45 and takes 11h 12m.
The fastest way to get from La Serena to Antofagasta Region is to fly which takes 1h 18m and costs $40 - $170.
No, there is no direct bus from La Serena to Antofagasta Region. However, there are services departing from Terminal de buses La Serena and arriving at George Washington esq. Arturo Prat via Pedro Aguirre Cerda esq. Liparita. The journey, including transfers, takes approximately 11h 12m.
The distance between La Serena and Antofagasta Region is 723 km. The road distance is 845.4 km.
The best way to get from La Serena to Antofagasta Region without a car is to bus via Antofagasta which takes 11h 12m and costs $25 - $45.
It takes approximately 1h 18m to fly from La Florida Airport (LSC) to Antofagasta Airport (ANF), including transfers and time at the airport.
La Serena to Antofagasta Region bus services, operated by Cormar, depart from Terminal de buses La Serena station.
The best way to get from La Serena to Antofagasta Region is to fly which takes 1h 18m and costs $40 - $170. Alternatively, you can bus via Antofagasta, which costs $25 - $45 and takes 11h 12m.
The quickest flight from La Florida Airport Airport to Antofagasta Airport Airport is the direct flight which takes 1h 18m.
La Serena to Antofagasta Region bus services, operated by Cormar, arrive at Antofagasta station.
What companies run services between La Serena, Chile and Antofagasta Region, Chile?
Sky Airline, JetSMART, and LATAM Chile fly from La Florida Airport (LSC) to Antofagasta Airport (ANF) 3 times a day. Alternatively, Cormar operates a bus from Terminal de buses La Serena to Antofagasta every 4 hours. Tickets cost $24–45 and the journey takes 10h 48m.
- Website
- jetsmart.com
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 21m
- When
- Tuesday, Friday, Wednesday, Thursday, Sunday, and Monday
- Estimated price
- $40–170
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 30m
- When
- Wednesday, Thursday, Monday, Tuesday, Sunday, and Friday
- Estimated price
- $30–180
- Website
- skyairline.com
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 19m
- When
- Sunday, Monday, and Wednesday
- Estimated price
- $50–230
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 27m
- When
- Sunday, Wednesday, Tuesday, and Monday
- Estimated price
- $40–230
- Website
- latam.com
Flights from La Florida Airport to Antofagasta Airport
- Ave. Duration
- 1h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–480
Flights from La Florida Airport to Calama Airport
- Ave. Duration
- 1h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–200
Bus from Terminal de buses La Serena to Antofagasta
- Ave. Duration
- 10h 48m
- Frequency
- Every 4 hours
- Estimated price
- $24–45
- Schedules at
- Cormar
- Website
- Flixbus Chile
Bus from Terminal de buses La Serena to Antofagasta
- Ave. Duration
- 11h 35m
- Frequency
- Every 3 hours
- Estimated price
- $80–140
- Schedules at
- Flixbus Chile
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal de buses La Serena to Antofagasta
- Ave. Duration
- 12h 30m
- Frequency
- 4 times a day
- Estimated price
- $35–45
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $35–45
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 12h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–50
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $35–45
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 11h 46m
- Frequency
- Twice daily
- Estimated price
- $20–35
- Book at
- Recorrido Pluss Chile
- Semi Cama
- $20–26
- Cama
- $29–35
- [email protected]
- Website
- Pullman San Andres
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 12h
- Frequency
- Hourly
- Estimated price
- $45–75
- Schedules at
- Pullman San Andres
- Semi Cama
- $45–65
- Cama
- $50–75
- [email protected]
- Website
- ciktur.cl
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 11h 40m
- Frequency
- 6 times a week
- Estimated price
- $35–50
- Schedules at
- kupos.cl
- Cama
- $40–50
- Semi Cama
- $35–45
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 13h 50m
- Frequency
- Every 4 hours
- Estimated price
- $23–80
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $23–35
- Cama
- $35–50
- Premium
- $65–80
- [email protected]
- Website
- facebook.com
Bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 10h 58m
- Frequency
- 4 times a week
- Estimated price
- $34
- Schedules at
- facebook.com
- Book at
- facebook.com
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More Questions & Answers
Yes, the driving distance between La Serena to Antofagasta Region is 845 km. It takes approximately 10h 48m to drive from La Serena to Antofagasta Region.
LATAM Chile, Sky Airline and JetSMART offer flights from La Florida Airport Airport to Antofagasta Airport Airport.
There are 332+ hotels available in Antofagasta Region.

















