There are 5 ways to get from La Serena to Arequipa by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Rodríguez Ballón International Airport
best- Fly from La Florida Airport (LSC) to Rodríguez Ballón International Airport (AQP)plane LSC - AQP
9h 19m$180–572Bus
cheapest- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Arequipabus
28h 6m$55–110Drive 1,929.6 km
- Drive from La Serena to Arequipacar 1,929.6 km
25h 8m$290–419Fly to Chacalluta Arica Airport, bus
- Fly from La Florida Airport (LSC) to Chacalluta Arica Airport (ARI)plane LSC - ARI
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Moqueguabus
- Take the bus from Moquegua to Arequipabus
8h 47m$169–347Bus #2
- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Arequipabus
28h 6m$77–136
La Serena to Arequipa by bus
Questions & Answers
The cheapest way to get from La Serena to Arequipa is to bus which costs $55 - $110 and takes 28h 6m.
The fastest way to get from La Serena to Arequipa is to fly and bus which takes 8h 47m and costs $160 - $350.
No, there is no direct bus from La Serena to Arequipa. However, there are services departing from Terminal de buses La Serena and arriving at Arequipa via Terminal Internacional and Tacna. The journey, including transfers, takes approximately 28h 6m.
The distance between La Serena and Arequipa is 1519 km. The road distance is 1929.6 km.
The best way to get from La Serena to Arequipa without a car is to bus which takes 28h 6m and costs $55 - $110.
It takes approximately 9h 19m to get from La Serena to Arequipa, including transfers.
La Serena to Arequipa bus services, operated by Turbus, depart from Terminal de buses La Serena station.
The best way to get from La Serena to Arequipa is to fly which takes 9h 19m and costs $180 - $600. Alternatively, you can bus, which costs $55 - $110 and takes 28h 6m.
La Serena to Arequipa bus services, operated by Turbus, arrive at Terminal Rodoviario de Arica station.
Arequipa is 1h behind La Serena. It is currently 1:03 AM in La Serena and 12:03 AM in Arequipa.
What companies run services between La Serena, Chile and Arequipa, Peru?
LATAM Chile, Sky Airline, and JetSMART fly from La Florida Airport (LSC) to Rodríguez Ballón International Airport (AQP) once daily. Alternatively, you can take a bus from Terminal de buses La Serena to Arequipa via Terminal Rodoviario de Arica, Terminal Internacional, and Tacna in around 28h 6m.
- Website
- latam.com
Flights from La Florida Airport to Rodríguez Ballón International Airport via Santiago, Lima
- Ave. Duration
- 12h 26m
- When
- Wednesday to Saturday
- Estimated price
- $220–750
Flights from La Florida Airport to Chacalluta Arica Airport via Santiago
- Ave. Duration
- 4h 42m
- When
- Thursday and Tuesday
- Estimated price
- $130–270
- Website
- jetsmart.com
Flights from La Florida Airport to Rodríguez Ballón International Airport via Santiago, Lima
- Ave. Duration
- 14h 36m
- When
- Thursday
- Estimated price
- $190–650
Flights from La Florida Airport to Chacalluta Arica Airport
- Ave. Duration
- 2h 3m
- When
- Friday, Sunday, Saturday, and Monday
- Estimated price
- $80–350
- Website
- skyairline.com
Flights from La Florida Airport to Rodríguez Ballón International Airport via Santiago, Lima
- Ave. Duration
- 13h 59m
- When
- Wednesday
- Estimated price
- $170–600
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $35–55
- Cama
- $60–85
- Premium
- $65–85
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 35m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Book at
- https://www.recorrido.cl/pluss-chile/en
- Semi Cama
- $30–45
- Cama
- $49–55
- Phone
- +56 57 226 9210
- [email protected]
- Website
- busesramoscholele.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 24h 15m
- Frequency
- Once daily
- Estimated price
- $30–52
- Schedules at
- busesramoscholele.cl
- Semi cama
- $30–45
- Salón cama
- $48–52
- Phone
- +56 58 222 8603
- [email protected]
- Website
- recorrido.cl
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
- Phone
- +51 953 954 708
- [email protected]
- Website
- redbus.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
Bus from Tacna to Moquegua
- Ave. Duration
- 1h 10m
- Frequency
- Every 3 hours
- Schedules at
- redbus.pe
Bus from Moquegua to Arequipa
- Ave. Duration
- 1h 5m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
- Phone
- +51 982 803 213
- [email protected]
- Website
- heroesdelpacifico.embarcar.com.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $18
- Schedules at
- heroesdelpacifico.embarcar.com.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $18
- Schedules at
- heroesdelpacifico.embarcar.com.pe
- [email protected]
- Website
- hallpa.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- hallpa.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- hallpa.pe
- Phone
- +51 511 418 1111
- [email protected]
- Website
- civa.com.pe
Bus from Tacna to Moquegua
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–50
- Schedules at
- civa.com.pe
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- Hourly
- Estimated price
- $70–110
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $70–100
- Cama
- $80–110
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 45m
- Frequency
- 5 times a day
- Estimated price
- $55–72
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
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More Questions & Answers
Yes, the driving distance between La Serena to Arequipa is 1930 km. It takes approximately 25h 8m to drive from La Serena to Arequipa.
There are 483+ hotels available in Arequipa.


























