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How to get fromLa Serena to Boliviaby plane, bus (Flixbus), car, or bus

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There are 6 ways to get from La Serena to Bolivia by plane, bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to El Alto International Airport

    best
    1. Fly from La Florida Airport (LSC) to El Alto International Airport (LPB)plane plane LSC - LPB
    8h 10m
    $110–400

  2. Bus via Antofagasta

    cheapest
    1. Take the bus from Terminal de buses La Serena to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus Calama / ...
    2. Take the bus from Terminal de Buses Cardenal Carlos Oviedo Cavada to Santa Cruzbus bus Santa Cruz
    34h 35m
    $62–118

  3. Bus

    1. Take the bus from Terminal de buses La Serena to Rodovario de Iquiquebus bus Santiago- Iquique / ...
    2. Take the bus from Iquique to Santa Cruzbus bus Santa Cruz
    32h 10m

  4. Drive 2,204.4 km

    1. Drive from La Serena to Santa Cruz de la Sierracar car 2,204.4 km
    30h 16m
    $272–393

  5. Fly to Viru Viru International Airport

    1. Fly from La Florida Airport (LSC) to Viru Viru International Airport (VVI)plane plane LSC - VVI
    6h 50m
    $315–451

  6. Bus via Uyuni

    1. Take the bus from Terminal de buses La Serena to Terminal Rodoviario Calamabus bus
    2. Take the bus from Terminal Rodoviario Calama to Uyunibus bus
    3. Take the bus from Uyuni to Sucrebus bus
    4. Take the bus from Sucre to Samaipatabus bus
    5. Take the bus from Samaipata to Santa Cruzbus bus
    42h 6m
    $115–195

La Florida Airport (LSC) to El Alto International Airport (LPB) flights

Calendar4Weekly Planes
Duration9h 46mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from La Serena to Bolivia.ExpandLaunch map view
  • Distance: 1,522.5 km
  • Duration: 8h 10m

What companies run services between La Serena, Chile and Bolivia?

LATAM Chile, Sky Airline, and Boliviana de Aviación fly from La Florida Airport (LSC) to El Alto International Airport (LPB) 4 times a week. Alternatively, you can take a bus from Terminal de buses La Serena to Santa Cruz de la Sierra via Iquique and Santa Cruz in around 32h 10m.

Airlines
Bus operators

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