There are 6 ways to get from La Serena to Cusco by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ)plane LSC - CUZ
8h 4m$130–460Bus #2
cheapest- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna Bus Station to Cusco Bus Stationbus
41h 21m$86–151Bus
- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Arequipabus
- Take the bus from Arequipa to Cuscobus
34h 36mDrive 2,384.1 km
- Drive from La Serena to Cuscocar 2,384.1 km
32h 46m$359–518Bus via Moquegua
- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Moqueguabus
- Take the bus from Moquegua to Arequipabus
- Take the bus from Arequipa to Cuscobus
35h 36mBus via El Alto
- Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to La Pazbus
- Take the bus from La Paz to Cuscobus
2d$119–226
La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ) flights
Questions & Answers
The cheapest way to get from La Serena to Cusco is to bus which costs $85 - $160 and takes 41h 21m.
The fastest way to get from La Serena to Cusco is to fly which takes 8h 4m and costs $130 - $460.
No, there is no direct bus from La Serena to Cusco. However, there are services departing from Terminal de buses La Serena and arriving at Cusco via Terminal Internacional, Tacna and Arequipa. The journey, including transfers, takes approximately 34h 36m.
The distance between La Serena and Cusco is 1823 km. The road distance is 2384.1 km.
The best way to get from La Serena to Cusco without a car is to bus which takes 34h 36m and costs .
It takes approximately 8h 4m to fly from La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ), including transfers and time at the airport.
La Serena to Cusco bus services, operated by Pullman San Andres, depart from Terminal de buses La Serena station.
The best way to get from La Serena to Cusco is to fly which takes 8h 4m and costs $130 - $460. Alternatively, you can bus, which costs and takes 34h 36m.
There is no direct flight from La Florida Airport Airport to Alejandro Velasco Astete International Airport Airport. The quickest flight takes 8h 4m and has one stopover.
La Serena to Cusco bus services, operated by Pullman San Andres, arrive at Terminal Rodoviario de Arica station.
What companies run services between La Serena, Chile and Cusco, Peru?
LATAM Chile, JetSMART, and Sky Airline fly from La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ) twice daily. Alternatively, you can take a bus from Terminal de buses La Serena to Cusco via Terminal Rodoviario de Arica, Terminal Internacional, Tacna, and Arequipa in around 34h 36m.
- Website
- latam.com
Flights from La Florida Airport to Alejandro Velasco Astete International Airport via Santiago
- Ave. Duration
- 11h 15m
- When
- Friday
- Estimated price
- $150–550
Flights from La Florida Airport to Alejandro Velasco Astete International Airport via Santiago, Lima
- Ave. Duration
- 9h 27m
- When
- Every day
- Estimated price
- $180–600
- Website
- skyairline.com
Flights from La Florida Airport to Alejandro Velasco Astete International Airport via Santiago, Lima
- Ave. Duration
- 13h 52m
- When
- Wednesday
- Estimated price
- $130–460
- Website
- jetsmart.com
Flights from La Florida Airport to Alejandro Velasco Astete International Airport via Santiago, Lima
- Ave. Duration
- 12h 39m
- When
- Thursday
- Estimated price
- $150–550
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $35–55
- Cama
- $60–85
- Premium
- $70–85
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 35m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Book at
- https://www.recorrido.cl/pluss-chile/en
- Semi Cama
- $30–45
- Cama
- $50–55
- Phone
- +56 57 226 9210
- [email protected]
- Website
- busesramoscholele.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 24h 15m
- Frequency
- Once daily
- Estimated price
- $30–53
- Schedules at
- busesramoscholele.cl
- Semi cama
- $30–45
- Salón cama
- $48–53
- Phone
- +56 58 222 8603
- [email protected]
- Website
- recorrido.cl
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
- Phone
- +51 953 954 708
- [email protected]
- Website
- redbus.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
Bus from Tacna to Moquegua
- Ave. Duration
- 1h 10m
- Frequency
- Every 3 hours
- Schedules at
- redbus.pe
Bus from Moquegua to Arequipa
- Ave. Duration
- 1h 5m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
- Phone
- +51 982 803 213
- [email protected]
- Website
- heroesdelpacifico.embarcar.com.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $18
- Schedules at
- heroesdelpacifico.embarcar.com.pe
- [email protected]
- Website
- hallpa.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- hallpa.pe
- Phone
- +51 993 585 217
Bus from Arequipa to Cusco
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
Bus from Arequipa to Cusco
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- Hourly
- Estimated price
- $75–120
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $75–100
- Cama
- $80–120
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- Hourly
- Estimated price
- $75–120
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $75–100
- Cama
- $80–120
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 23h 25m
- Frequency
- Hourly
- Estimated price
- $75–120
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $75–100
- Cama
- $80–120
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 45m
- Frequency
- 5 times a day
- Estimated price
- $55–73
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 45m
- Frequency
- 5 times a day
- Estimated price
- $55–73
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
Bus from Terminal de buses La Serena to Terminal Rodoviario de Arica
- Ave. Duration
- 22h 45m
- Frequency
- 5 times a day
- Estimated price
- $55–73
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $55–65
- Phone
- +51 511 418 1111
- [email protected]
- Website
- civa.com.pe
Bus from Tacna to Moquegua
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $20–50
- Schedules at
- civa.com.pe
- Phone
- +51 051 602 943
- Website
- facebook.com
Bus from Tacna Bus Station to Cusco Bus Station
- Ave. Duration
- 15h 30m
- Frequency
- Twice daily
- Estimated price
- $25–35
- Schedules at
- facebook.com
- Phone
- +51 2228 7749
- [email protected]
- Website
- facebook.com
Bus from Terminal Internacional to La Paz
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $18
- Schedules at
- facebook.com
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Terminal Internacional to La Paz
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $23–300
- Book at
- https://www.ticketsbolivia.com/company/nc_internacional.php
Bus from La Paz to Cusco
- Ave. Duration
- 14h
- Frequency
- Twice daily
- Estimated price
- $40–340
- Book at
- https://www.ticketsbolivia.com/company/nc_internacional.php
- Phone
- +56 995369884
- Website
- facebook.com
Bus from Terminal Internacional to La Paz
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $10
- Schedules at
- facebook.com
- Phone
- +597 ,
- Website
- facebook.com
Bus from Terminal Internacional to La Paz
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Estimated price
- $18
- Book at
- ticketsbolivia.com.bo
- Phone
- +591 72492788
- [email protected]
- Website
- trans-salvador.com
Bus from Terminal Internacional to La Paz
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- https://trans-salvador.com/inicioEn.php
- Phone
- +591 2 228 1920
- [email protected]
- Website
- facebook.com
Bus from La Paz to Cusco
- Ave. Duration
- 15h
- Frequency
- Once daily
- Estimated price
- $45
- Schedules at
- redbus.pe
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More Questions & Answers
Cusco is 1h behind La Serena. It is currently 4:07 AM in La Serena and 3:07 AM in Cusco.
Yes, the driving distance between La Serena to Cusco is 2384 km. It takes approximately 32h 46m to drive from La Serena to Cusco.
JetSMART, Sky Airline and LATAM Chile offer flights from La Florida Airport Airport to Alejandro Velasco Astete International Airport Airport.
Book your La Serena to Cusco bus tickets online with 12go.asia.
There are 1403+ hotels available in Cusco.














































