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How to get fromLa Serena to Cuscoby plane, bus, or car

Find Transport to Cusco

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There are 6 ways to get from La Serena to Cusco by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ)plane plane LSC - CUZ
    7h 33m
    $110–400

  2. Bus #2

    cheapest
    1. Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna Bus Station to Cusco Bus Stationbus bus
    40h 41m
    $82–145

  3. Bus

    1. Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna to Arequipabus bus
    4. Take the bus from Arequipa to Cuscobus bus
    34h 36m

  4. Drive  2,404.7 km

    1. Drive from La Serena to Cuscocar car 2,404.7 km
    34h
    $364–526

  5. Bus via Moquegua

    1. Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to Tacnabus bus
    3. Take the bus from Tacna to Moqueguabus bus
    4. Take the bus from Moquegua to Arequipabus bus
    5. Take the bus from Arequipa to Cuscobus bus
    34h 56m

  6. Bus via El Alto

    1. Take the bus from Terminal de buses La Serena to Terminal Rodoviario de Aricabus bus
    2. Take the bus from Terminal Internacional to La Pazbus bus
    3. Take the bus from La Paz to Cuscobus bus
    47h 45m
    $115–219

La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ) flights

Calendar24Weekly Planes
Duration9h 49mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from La Serena to Cusco.ExpandLaunch map view
  • Distance: 1,822.9 km
  • Duration: 7h 33m

What companies run services between La Serena, Chile and Cusco, Peru?

Sky Airline and LATAM Chile fly from La Florida Airport (LSC) to Alejandro Velasco Astete International Airport (CUZ) 3 times a day. Alternatively, you can take a bus from Terminal de buses La Serena to Cusco via Terminal Rodoviario de Arica, Terminal Internacional, Tacna, and Arequipa in around 34h 36m.

Airlines
Bus operators

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